The fifth day of the French Open was another roller-coaster one, as seven seeded players bit the dust.It was business as usual for World No. 1 Iga Swiatek, who steamrolled past Alison Riske for her 30th straight win. Another tournament favourite, third seed Paula Badosa, also advanced to the third round. However, that was not the case for two former champions, who went out in three sets.Roland-Garros@rolandgarrosThe @iga_swiatek train rolls on Catch the world No.1's latest journey @Emirates | #EmiratesFlyBetterMoments | #RolandGarros15716The @iga_swiatek train rolls on 🚂Catch the world No.1's latest journey 👇@Emirates | #EmiratesFlyBetterMoments | #RolandGarros https://t.co/GrLEepVITYOn the men's side, the retiring Gilles Simon wooed the Roland Garros faithful, downing American Steve Johnson to bring up his 500th singles match win. Elsewhere, second seed Daniil Medvedev and fourth seed Stefanos Tsitsipas took contrasting routes to the Round of 32. However, three seeds fell by the wayside.On that note, here's a look at the five biggest upsets on Day 5 of the 2022 French Open:#1 Shelby Rogers beats (9) Danielle Collins 6-4, 6-3Danielle Collins at the 2022 French Open - Day FiveDanielle Collins failed to get past her compatriot Shelby Rogers in an all-American second-round matchup at the French Open on Thursday.Rogers burst out of the gates, finding herself 4-0 up against the ninth seed. Although Collins reduced the arrears, Rogers recovered to take the set 6-4.It was more of the same in the second, with Rogers taking a 5-1 lead. However, a lapse in concentration allowed Collins to pull two games back before Rogers recorded her second top-10 win of the year, sixth overall.Ben Rothenberg@BenRothenbergAnother top-10 seed out:Shelby Rogers takes out #9 Danielle Collins 6-4, 6-3.#RolandGarros15613Another top-10 seed out:Shelby Rogers takes out #9 Danielle Collins 6-4, 6-3.#RolandGarrosThe World No. 50 will take on 20th seed Daria Kasatkina on Saturday for a place in the second week.#2 Leolia Jeanjean beats (8) Karolina Pliskova 6-2, 6-2Karolina Pliskova at the 2022 French Open - Day FiveKarolina Pliskova was the biggest casualty on the fifth day of the French Open.The lanky Czech, seeded eighth, received an absolute hiding from World No. 227 Leolia Jeanjean, who notched up her first top-10 win in the process. Jeanjean, playing in her first main draw, surged past the finish line in just 75 minutes, dropping only two games in each set.Roland-Garros@rolandgarros Wildcard wonder In her maiden Grand Slam, world No.227 Leolia Jeanjean upsets No.8 seed Karolina Pliskova 6-2, 6-2 for a first career top 10 win and third round#RolandGarros16529🇫🇷 Wildcard wonder 🇫🇷In her maiden Grand Slam, world No.227 Leolia Jeanjean upsets No.8 seed Karolina Pliskova 6-2, 6-2 for a first career top 10 win and third round#RolandGarros https://t.co/N01ZHyC2K2In the process, Jeanjean became the lowest-ranked player in 34 years to beat a top-10 player at Roland Garros. She'll play Irina-Camelia Begu for a place in the fourth round.#3 Mackenzie McDonald beats (22) Nikoloz Basilashvili 6-3, 6-1, 6-4Nikoloz Basilashvili at the 2022 French Open - Day FiveNikoloz Basilashvili was the highest men's seed that fell on the fifth day of the French Open.The 22nd seed was second-best for most of his second-round match against Mackenzie McDonald, winning just three games in the opener. The American was even more clinical in the second, dropping a single game to take a two-set lead. Basilashvili provided sterner competition in the third but conceded defeat in a contest that lasted seven minutes shy of two hours.Ben Rothenberg@BenRothenbergNice and decisive win for Mackie McDonald, beating #22 Basilashvili 6-3, 6-1, 6-4.#RolandGarros49Nice and decisive win for Mackie McDonald, beating #22 Basilashvili 6-3, 6-1, 6-4.#RolandGarrosMcDonald will play 11th seed Jannik Sinner for a place in the second week.#4 Alize Cornet beats (13) Jelena Ostapenko 6-0, 1-6, 6-3Jelena Ostapenko at the 2022 French Open - Day ThreeJelena Ostapenko has failed to live up to expectations at Roland Garros following her spectacular run to the title five years ago.The 13th seed started off against Alize Cornet on the worst possible note, losing a bagel set. To her credit, the 2017 champion burst into life, winning the second 6-1 to force a decider.However, Cornet regained her mojo in the third set, saving four break points to hold for 2-0. The Frenchman broke again at 5-3 as Ostapenko fell before the second week at Roland Garros for the fifth straight year. The Latvian has lost thrice in the first round and once each in the second and third rounds since winning the tournament in 2017.Roland-Garros@rolandgarrosAllez @alizecornet knocks out 2017 champion in Jelena Ostapenko 6-0, 1-6, 6-3 to progress to the third round.#RolandGarros28843Allez 🇫🇷@alizecornet knocks out 2017 champion in Jelena Ostapenko 6-0, 1-6, 6-3 to progress to the third round.#RolandGarros https://t.co/rfQDvfwMwJCornet, making a 61st consecutive Grand Slam main-draw appearance, will face Qinwen Zheng, who upset another former Roland Garros champion on the day.#5 Qinwen Zheng beats (19) Simona Halep 2-6, 6-2, 6-1Qinwen Zheng exults after beating Simona Halep at the 2022 French Open - Day FiveQinwen Zheng provided one of the biggest upsets at Roland Garros this year when the 19-year-old sent 2018 champion Simona Halep packing.Halep looked to be in control of the contest after she dropped only two games in the opener and broke for 2-1 in the second. However, the 19-year-old Zheng caught fire, and an ailing Halep could muster no response.After recouping the break, Zheng would drop only one game in the remainder of the match to notch up the biggest win of her career on Court Simonne-Mathieu.Roland-Garros@rolandgarrosLearning on the job In just her second major, 19-year-old Qinwen Zheng eliminates 2018 champion Halep 2-6, 6-2, 6-1#RolandGaroos53982Learning on the job 📈In just her second major, 19-year-old Qinwen Zheng eliminates 2018 champion Halep 2-6, 6-2, 6-1#RolandGaroos https://t.co/pVLuY7Ae0bPlaying only her second main draw at a Grand Slam, Zheng will take on home favourite Alize Cornet, who took out 2017 champion Jelena Ostapenko earlier in the day.