Venus Williams put in a valiant effort upon her return to Cincinnati on Tuesday, but it wasn't enough to progress past the first round of the Western & Southern Open.Karolina Pliskova easily defeated the 42-year-old American. For the first time in five years, two former World No. 1's faced off and with the win, Pliskova improved her head-to-head record against Williams to 3-1.The Czech won a chaotic first set 7-5. Williams' second-serve percentage significantly deteriorated in the second set, allowing Pliskova to cruise to a 7-5, 6-1 win.wta@WTAUp and running in Cincy Former champion @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis20428Up and running in Cincy 👉Former champion 🇨🇿 @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis https://t.co/DoiH8EUmgJTennis fans expressed their disappointment at the American's loss on Twitter, with the majority advising her to retire along with her younger sister, Serena Williams.One user opined that Venus Williams was "done" and that she needed to retire after the US Open, and wrote:"Venus is done -- she needs to retire after the USOPEN with Serena - she can no longer win on the tour - father time has said its time - next stop HOF along with her sister - they should retire together then go into the HOF together only fitting."sal l@salroughcuts@WTA @KaPliskova Venus is done -- she needs to retire after the USOPEN with Serena - she can no longer win on the tour - father time has said its time - next stop HOF along with her sister - they should retire together then go into the HOF together only fitting -5@WTA @KaPliskova Venus is done -- she needs to retire after the USOPEN with Serena - she can no longer win on the tour - father time has said its time - next stop HOF along with her sister - they should retire together then go into the HOF together only fitting -Williams' age was brought up by another user, who suggested that it was time to retire. The user said:"Venus Williams is 42 years old, it's time go."melende@melende2000@PlaylistRequest @WTA @KaPliskova @Venuseswilliams @PlaylistRequestVenus Williams is 42 years old, it's time go@PlaylistRequest @WTA @KaPliskova @Venuseswilliams @PlaylistRequestVenus Williams is 42 years old, it's time goAnother account wrote that although the American is a great champion, "her time has passed.""Venus needs to retire her time has passed. She is a great champion but she isn't competitive anymore," the user wrote.OrvilleLloydDouglas🇨🇦🏳️‍🌈@OrvilleLloyd@WTA @KaPliskova Venus needs to retire her time has passed. She is a great champion but she isn't competitive anymore.2@WTA @KaPliskova Venus needs to retire her time has passed. She is a great champion but she isn't competitive anymore.Here are a few more reactions:melende@melende2000@WTA @KaPliskova Venus Williams should retire4@WTA @KaPliskova Venus Williams should retireDude@TheBar 🧉 🍺@PlaylistRequest@melende2000 @WTA @KaPliskova Osaka lost 2 1st rounders in a row, same as Venus and Venus played higher quality players so I don't feel bad bout her losing.She like Osaka need some match toughness which is play more often.They both great players.You should retire from Twitter dude!@Venuseswilliams32@melende2000 @WTA @KaPliskova Osaka lost 2 1st rounders in a row, same as Venus and Venus played higher quality players so I don't feel bad bout her losing.She like Osaka need some match toughness which is play more often.They both great players.You should retire from Twitter dude!@VenuseswilliamsRival de Marte@RivaldeMarte@WTA @KaPliskova Wow, former champion?aka she won last year or last edition 🤔 @CincyTennis #PodjKaja @WTA @KaPliskova Wow, former champion?aka she won last year or last edition 🤔 @CincyTennis #PodjKaja 💜Jorge Luis Lozano Salazar@JorgeLu59746800@WTA @KaPliskova Retirement of the Williams?@WTA @KaPliskova Retirement of the Williams?Also Checkout:- Cincinnati Open 2022 ScheduleCristian Paunescu@Cris_Paunescu@WTA @KaPliskova Another wildcard wasted...@WTA @KaPliskova Another wildcard wasted...Marcos Rodrigues 🏎️@marcorodrigueo@WTA @KaPliskova @WTA @KaPliskova 👎👎👎👎👎marcoruza@sloanepowerTHE SALTY HANDSHAKE twitter.com/wta/status/155…wta@WTAUp and running in Cincy Former champion @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis20328Up and running in Cincy 👉Former champion 🇨🇿 @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis https://t.co/DoiH8EUmgJTHE SALTY HANDSHAKE twitter.com/wta/status/155…thal@thalissufferingVee🥺 im sad twitter.com/WTA/status/155…wta@WTAUp and running in Cincy Former champion @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis20328Up and running in Cincy 👉Former champion 🇨🇿 @KaPliskova secures a spot in the second round with a 7-5, 6-1 win over Venus Williams.#CincyTennis https://t.co/DoiH8EUmgJVee💔🥺 im sad twitter.com/WTA/status/155…choo choo@beedadoobopstress watching venus williamsstress watching venus williamsVenus Williams' 2022 season so farWilliams at the National Bank Open Toronto - Day 3Earlier in June, Venus Williams made a return to the WTA tour after an eleven-month hiatus, spurred on by her sister Serena Williams. She teamed up with Andy Murray's brother Jamie Murray to play mixed doubles at the 2022 Wimbledon Championships.However, their run was cut short in the second round by the pairing of Alicia Barnett and Jonny O'Mara, who won 3-6, 6-4, 7-6(18-16). The entertaining match between the two wildcard teams lasted two hours and 12 minutes on Court 2.Tennis Channel@TennisChannelWelcome back, Venus. @Venuseswilliams | #Wimbledon4288332Welcome back, Venus. 💚💜@Venuseswilliams | #Wimbledon https://t.co/fdOjq0RYwYWilliams then made her singles return at the 2022 Citi Open, but fell to Rebecca Marino, 4-6, 6-1, 6-4, in the Round of 32. This was followed by another disappointing performance at the Canadian Open where she fell to Jil Teichmann in straight sets, 6-2, 6-3.It isn't yet clear if Williams will play at the US Open, but if she does, it will be her first Major singles event since losing to Ons Jabeur in the second round of Wimbledon 2021.