Match DetailsFixture: (28) John Isner vs Yoshihito NishiokaDate: 29 June 2021Tournament: The Championships, WimbledonRound: First round (Round of 128)Venue: London, Great BritainCategory: Grand SlamSurface: GrassPrize money: £17,066,000Live telecast: USA - Tennis Channel | UK - BBC TV & Radio | India - Star Sports / Disney+ Hotstar VIP.Today, our gates are open ☺️#WimbledonThing pic.twitter.com/ePQ6URnMqQ— Wimbledon (@Wimbledon) June 28, 2021John Isner vs Yoshihito Nishioka PreviewJohn Isner hasn't played much tennis this season and will have tempered expectations at Wimbledon, where he begins his campaign against Japan's Yoshihito Nishioka on Tuesday.The American has a 9-5 record this year, which includes quarterfinal runs in Madrid and Delray Beach. Seeded 28th at Wimbledon, Isner is coming off a third-round defeat to eventual finalist Stefanos Tsitsipas at Roland Garros.Isner is yet to play a match on grass this year, but will fancy his chances at Wimbledon, where he reached the semifinals in 2018. The American has won four (all at Newport) of his 15 career titles on grass, which shows he enjoys playing on the slick surface.Yoshihito Nishioka, meanwhile, has won only eight of his 21 matches this year. The left-hander arrives at Wimbledon following a first-round loss to Andreas Seppi at Eastbourne.Nishioka's only career title came on the hardcourts of Shenzhen three years ago and he has won only 10 Grand Slam matches in his career.John Isner vs Yoshihito Nishioka head-to-headIn their only previous meeting on tour, Isner beat Nishioka in three sets in the Round of 16 in Memphis four years ago. Thus, the American leads the head-to-head 1-0.John Isner vs Yoshihito Nishioka predictionConsidering the gulf in class and experience between the two players, especially on the big stage, Isner will start as the overwhelming favorite. The tall American has a game well suited to fast surfaces like grass, where his booming serves and powerful groundstrokes do plenty of damage.Meanwhile, the diminutive Nishioka is a counterpuncher with a decent lefty serve that could drag Isner wide on the ad court. The unseeded Japanese will also look to move the tall American from side to side and prevent him gaining control of the points. However, that could be a tall order considering Isner's firepower.#BREAKING: All England Club says #Wimbledon will introduce fifth-set tiebreakers starting next year.No more long matches for @JohnIsner 😢— Sean O'Reilly (@SeanWFTS) October 19, 2018Nishioka has not won a match at Wimbledon in three attempts, so beating an experienced campaigner like Isner on grass is not very likely.Prediction: John Isner to win in straight sets