#4 The Joker (WrestleMania 25)

Sometimes, to defeat a monster, you must become a monster. And that was clear when Rey took on one of WWE's most villainous men, John 'Bradshaw' Layfield at WrestleMania 25.
In a tribute to the late Heath Ledger, who had died months prior, Mysterio channeled his dark side, dressing as iconic supervillain the Joker, who Ledger played in 2008's 'The Dark Knight'.
R-Truth wanted to 'kill' former WWE writer. More details HERE
With the mad clown's signature Purple and Green aesthetic, Mysterio completed the look with a chalk-white mask and red 'scars'.
It must've helped, as Mysterio defeated the Texan Billionaire in less than 30 seconds, claiming the Intercontinental Championship, with JBL quitting WWE shortly afterward.