Strikeout props are a popular way to bet on MLB games, offering a chance to capitalize on top pitchers' ability to rack up strikeouts. With a full slate of games taking place on June 11, there will be plenty of great options to choose from.
Some dominant arms will be taking the mound on Wednesday, but there are other pitchers that come with some value too. Here are some options to consider while placing your best bets.
Top MLB Pitchers Strikeouts Prop Bets for June 11, 2025

Walker Buehler: Over 4.5 (-105)

Walker Buehler will be starting for the Boston Red Sox on Wednesday night and he has an interesting matchup with the Tampa Bay Rays. Buehler is still one of the top MLB pitchers and he should have some success by striking out at least five batters.
Jesus Luzardo: Under 5.5 (-125)
Jesus Luzardo was off to a great start in the 2025 season, but he has given up a total of 20 earned runs in his last two starts. Luzardo is going to have a short leash in his matchup with the Chicago Cubs, and he will fail to reach six strikeouts in this start.
Casey Mize: Over 4.5 (-110)

Casey Mize is emerging as one of the top MLB pitchers, and he is facing a struggling Baltimore Orioles team on Wednesday night. Mize can wipe out opponents, and taking the over is the smart play based on the odds.
Safest Pick of the Day: Kyle Hendricks Over 3.5 (-145)

Kyle Hendricks continues to get outs as a veteran pitcher for the Los Angeles Angels, but he's not known as someone that strikes out many batters. The over/under number is set at just 3.5 strikeouts though, and he should get to at least four with ease.
Bold Prediction: Ben Brown Over 5.5 (+105)

Throwing in a bold prediction is a great way to cash in when making prop bets, and betting on young Ben Brown is the way to go on June 11. Brown has been great in his two most recent starts, and we expect him to strikeout at least six hitters in a matchup with the Philadelphia Phillies.