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#3 Edmundo Suarez - 20 goals
Edmundo Suarez, more popularly known as Mundo, scored many goals against Sevilla.
The late Valencia legend, a three-time La Liga winner with Los Che, is the club's all-time top scorer with 269 goals across competitions, including friendlies. That tally comprises 20 strikes against Los Nervionenses.
He netted a hat-trick against Sevilla in Valencia's triumphant La Liga campaign in 1941-42. Mundo bagged another hat-trick against the same opponents the next season. A third against Los Nervionenses followed in 1944-45.
#2 Cristiano Ronaldo - 27 goals
Cristiano Ronaldo is widely regarded as one of the best players to have graced the beautiful game.
A prolific scorer for club and country for nearly two decades, the 37-year-old particularly enjoyed scoring against Sevilla. His tally of 27 goals (in 18 games) against the Andalusians is the most the Portugal captain has netted against any opponent.
That tally comprises as many as five La Liga hat-tricks, including a stunning four-goal salvo in a 6-2 league win at Sevilla in 2010-11. After doubling his team's lead at the half-hour mark, the then 26-year-old scored three times in 12 minutes in the second half.
Apart from conceding 25 times in the league, Los Nervionenses also had to endure the might of Ronaldo in the UEFA Super Cup. The five-time Ballon d'Or winner netted twice against the Andalusians in the 2015 edition of the competition. Los Nervionenses managed to keep Ronaldo quiet only in the Copa Del Rey across two games.
#1 Lionel Messi - 38 goals
Lionel Messi, like Ronaldo, is another player who is widely regarded as one of the finest players to have played the game.
The Barcelona legend has scored over 750 goals for club and country during his illustrious career. That tally comprises a stunning 38 strikes (and 19 assists) in 43 games against Sevilla across four different tournaments. It's the most Messi has scored against a single opponent, with most of those strikes coming in La Liga.
The record seven-time Ballon d'Or winner has struck three hat-tricks against Los Nervionenses - two in the league and one in the Supercopa de Espana.
