Ajax are set to host Liverpool at the Johan Cruyff Arena on Wednesday in their opening UEFA Champions League fixture.Ajax come into this game on the back of a 5-1 thrashing of Heerenveen at the weekend in the Eredivisie. A brace from the captain and forward Dusan Tadic and goals from young Ghana international Mohammed Kudus, midfielder Davy Klaassen and Brazilian forward Antony sealed the win for Erik ten Hag's side.Forward Henk Veerman scored the consolation goal for Heerenveen.Two 20-year-olds on the scoresheet for Ajax today. 🔥🔥🇬🇭 Mohammed Kudus (1st Ajax goal, 2 assists)🇧🇷 Antony (3rd goal in 5 games)The Dutch club's latest young gems?#UCL pic.twitter.com/259daiImGG— UEFA Champions League (@ChampionsLeague) October 18, 2020Liverpool, on the other hand, drew 2-2 against Everton on Saturday in the English Premier League. A feisty derby encounter saw Senegal international Sadio Mane and winger Mohamed Salah score for Liverpool, with centre-back Michael Keane and in-form striker Dominic Calvert-Lewin finding the net for Everton.Forward Richarlison was sent off for Everton in the second half, complicating matters for Carlo Ancelotti's side.Ajax vs Liverpool Head-to-HeadAjax and Liverpool have not faced each other in a competitive fixture for some time now.Ajax form guide in the Eredivisie: W-W-W-L-WLiverpool form guide in the English Premier League: W-W-W-L-DAlso check out: Complete Champions League Schedule 2020/21Ajax vs Liverpool Team NewsAjax have no known injury issues, and manager Erik ten Hag is expected to have a fully-fit squad at his disposal.Injured: NoneDoubtful: NoneSuspended: NoneMeanwhile, Liverpool were dealt a heavy blow in their clash against Everton. Key centre-back Virgil van Dijk suffered a serious injury which could potentially keep him out of the team for the rest of the season. Goalkeeper Alisson Becker, midfielder Thiago Alcantara and England international Alex Oxlade-Chamberlain are all out.pic.twitter.com/rpdxFZViwq— Virgil van Dijk (@VirgilvDijk) October 18, 2020Injured: Virgil van Dijk, Alisson Becker, Thiago Alcantara, Alex Oxlade-ChamberlainDoubtful: NoneSuspended: NoneAlso check out: Complete Champions League Results and live Scores 2020/21Ajax vs Liverpool Predicted XIAjax Predicted XI (4-3-3): Andre Onana, Noussair Mazraoui, Perr Schuurs, Daley Blind, Nicolas Tagliafico, Ryan Gravenberch, Davy Klaassen, Mohammed Kudus, David Neres, Dusan Tadic, Quincy PromesLiverpool Predicted XI (4-3-3): Adrian, Trent Alexander-Arnold, Joel Matip, Joe Gomez, Andrew Robertson, Jordan Henderson, Fabinho, Georginio Wijnaldum, Mohamed Salah, Roberto Firmino, Sadio ManeAjax vs Liverpool PredictionAjax lost two key players in Donny van de Beek and Hakim Ziyech this summer, with the two joining Manchester United and Chelsea respectively. Young stars Ryan Gravenberch and Mohammed Kudus have begun their Ajax careers well, and will look to make an impact on the biggest stage.Liverpool, on the other hand, are still reeling after losing Virgil van Dijk to a long-term injury. In his absence, Joel Matip and Fabinho will have to step up and partner Joe Gomez. Thiago's absence could prove to be vital as well.Ajax will be the underdogs, but the absence of Alisson, van Dijk and Thiago could potentially cause an upset, and we are predicting a narrow win for the home side this week.Prediction: Ajax 2-1 LiverpoolFollow Sportskeeda to get the latest Champions League Draws and Final udpates 2020/21