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#3 Danilo D'Ambrosio (Inter Milan) vs Cristiano Ronaldo (Juventus)
Cristiano Ronaldo has almost single-handedly kept Juventus in the hunt for a top-four finish. So he'll be expected to produce another stellar display, this time against Inter Milan.
The man who will be most likely be charged with stopping the Madeira native would be Danilo D'Ambrosio. He will have to be at his best to keep Ronaldo, who is currently leading the Capocannoniere race, quiet.
Juventus have shown a penchant for crosses in recent weeks, which plays to Cristiano Ronaldo's strengths. This is an area where D'Ambrosio might struggle, as he is not the most physically imposing of defenders.
The Inter Milan defender's lack of pace could also see him exposed. But Conte's deployment of a three-man defence means Milan Skriniar could provide cover for D'Ambrosio.
#4 Alvaro Morata (Juventus) vs Stefan de Vrij (Inter Milan)
Alvaro Morata has not had the most spectacular of seasons, which has consequently seen him drift in and out of the Juventus starting lineup. However, with a lot riding on the outcome of this game against Inter Milan, Andrea Pirlo is likely to double up in attack to put pressure on the visitors' three-man backline.
Morata's strength is his aerial prowess, but the Spain international is also adept in holding up play and acting as an effective foil for Cristiano Ronaldo.
Either way, Stefan de Vrij would have to be up to the task of marking the former Chelsea man. Morata is also extremely physical but has tended to struggle against imposing defenders.
De Vrij, inarguably, has been one of the standout defenders in the Serie A this season. So Conte will count on him to produce another marquee display at the heart of the Inter Milan defence.
#5 Romelu Lukaku (Inter Milan) vs Giorgio Chiellini and Matthijs de Ligt (Juventus)
If Juventus hope to get anything from their game against Inter Milan, they will have to keep a tight leash on Romelu Lukaku.
The 28-year-old has been nothing short of phenomenal since arriving at the San Siro. He has taken his all-round game to new heights under the astute management of Antonio Conte.
Lukaku's directness and strength makes him a handful for defenders, while his penchant to score with his back to goal is something Juventus will have to be wary of.
In this regard, Giorgio Chiellini might struggle against Lukaku, as the Juventus captain does not possess the pace to keep hold of the former Manchester United man.
However, Juventus would bank on Chiellini's experience and Matthijs de Ligt's youthful energy and quality to keep Inter Milan's leading man quiet.
