The UEFA Europa League returns with a fresh set of fixtures as Real Betis welcome Eintracht Frankfurt to the Benito Villamarín Stadium in the first leg of their round-of-16 clash on Wednesday.The hosts had to see off Zenit St. Petersburg in the playoff round, while the Germans secured an impressive first-placed finish in the group stages. View this post on Instagram Instagram PostReal Betis failed to find their feet last weekend as they fell to a 4-1 humbling at the hands of Atletico Madrid on home turf.They have now failed to taste victory in any of their last four games, claiming two draws and losing two in that time.They now turn their sights to the Europa League, where they saw off a dogged Zenit St. Petersburg side 3-2 on aggregate. View this post on Instagram Instagram PostEintracht Frankfurt, meanwhile, returned to winning ways last Saturday as they edged out Hertha Berlin 4-1 in the Bundesliga.Prior to that, they were on a three-match losing streak, shipping four goals and scoring none in that time.Manager Oliver Glasner will now hope his side can build on that performance as they head to the Europa League, where they went unbeaten in the group stages, claiming three wins and three draws.Real Betis vs Eintracht Frankfurt Head-To-HeadThis will be the second-ever meeting between the two sides. Their first encounter came back in 2017, when Eintracht Frankfurt claimed a 3-0 friendly victory.Real Betis Form Guide: W-D-L-D-LEintracht Frankfurt Form Guide: W-L-L-L-WReal Betis vs Eintracht Frankfurt Team NewsReal BetisAndrés Guardado, Victor Camarasa, Juan Miranda, Álex Moreno and Martin Montoya are all recuperating from injuries and will sit out Wednesday’s game.Injured: Victor Camarasa, Juan Miranda, Álex Moreno, Martin Montoya, Andrés GuardadoSuspended: None View this post on Instagram Instagram PostEintracht FrankfurtThe Germans will be without the services of Danny da Costa, Sebastian Rode and Ragnar Ache, who have been sidelined through injuries. Gonçalo Paciência is suspended, but is also injured at the moment. Erik Durm and Stefan Ilsanker were both left out of their Europa League squad.Injured: Danny da Costa, Sebastian Rode, Ragnar AcheSuspended: Goncalo PaciênciaReal Betis vs Eintracht Frankfurt Predicted XIReal Betis Predicted XI (4-2-3-1): Claudio Bravo; Youssouf Sabaly, Germán Pezzella, Víctor Ruiz, Marc Bartra; William Carvalho, Guido Rodriguez; Sergio Canales, Nabil Fekir, Juanmi; Willian JoséEintracht Frankfurt Predicted XI (3-4-2-1): Kevin Trapp; Tuta, Martin Hinteregger, Evan N'Dicka; Ansgar Knauff, Djibril Sow, Kristijan Jakic, Filip Kostic; Daichi Kamada, Jesper Lindstrom; Rafael Santos BorreReal Betis vs Eintracht Frankfurt PredictionReal Betis have suffered a slump in form in recent weeks and will be looking to end this dry spell. The visitors, meanwhile, head into the game with renewed confidence after ending their losing streak last weekend. We predict the spoils will be shared in a high-scoring draw, leaving it all to play for in the second leg.Prediction: Real Betis 2-2 Eintracht Frankfurt