Sandhausen are set to play RB Leipzig at the BWT-Stadion am Hardtwald on Saturday in the first round of the DFB-Pokal.Sandhausen come into this game on the back of a 3-0 loss to Mersad Selimbegovic's Jahn Regensburg in the 2.Bundesliga. Goals from midfielder Carlo Boukhalfa, Canadian centre-back Scott Kennedy and Dutch forward Joel Zwarts ensured victory for Jahn Regensburg. Sandhausen had Senegalese defender Oumar Diakhite sent off in the second-half.RB Leipzig, on the other hand, drew 1-1 against Erik ten Hag's Ajax in a friendly game a few days ago. An early first-half goal from Serbian forward Dusan Tadic for Ajax was cancelled out by a second-half goal from French midfielder Christopher Nkunku for RB Leipzig.Sandhausen vs RB Leipzig Head-to-HeadIn four head-to-head encounters between the two sides, Sandhausen have won two games, lost one and drawn one.Big session ready for Saturday 💪⚽ 🔴⚪ #RBLeipzig #SVSRBL pic.twitter.com/lAtxSzXr8Z— RB Leipzig English (@RBLeipzig_EN) August 4, 2021The two clubs last faced each other in 2016 in the 2.Bundesliga, with Sandhausen beating RB Leipzig 1-0. A second-half goal from midfielder Korbinian Vollmann sealed the deal for Sandhausen.Sandhausen form guide in the 2.Bundesliga: L-LRB Leipzig form guide in the Bundesliga: yet to playSandhausen vs RB Leipzig Team NewsSandhausenSandhausen will be without veteran centre-back Tim Kister and winger Christian Kinsombi, while there are doubts over the availability of striker Pascal Testroet. Other than that there are no known issues and manager Gerhard Kleppinger is expected to have a fully fit squad at his disposal.Injured: Tim Kister, Christian KinsombiDoubtful: Pascal TestroetSuspended: NoneRB LeipzigMeanwhile, RB Leipzig manager Jesse Marsch will be unable to call upon the services of left-backs Marcelo Saracchi and left-back Marcel Halstenberg, as well as Germany international Benjamin Henrichs, while there are doubts over the availability of while there are doubts over the availability of German right-back Lukas Klostermann, South Korea international Hwang Hee-chan and Hungarian midfielder Dominik Szoboszlai.Spanish midfielder Dani Olmo is representing his nation at the 2020 Tokyo Olympics and is not available.Injured: Marcelo Saracchi, Marcel Halstenberg, Benjamin HenrichsDoubtful: Hwang Hee-chan, Dominik Szoboszlai, Lukas KlostermannSuspended: NoneNot available: Dani OlmoSandhausen vs RB Leipzig Predicted XISandhausen Predicted XI (3-4-3): Patrick Drewes, Dennis Diekmeier, Immanuel Hohn, Aleksandr Zhirov, Bashkim Ajdini, Julius Biada, Erik Zenga, Chima Okoroji, Cebio Soukou, Daniel Keita-Ruel, Alexander EssweinRB Leipzig Predicted XI (4-3-3): Peter Gulacsi, Nordi Mukiele, Willi Orban, Mohamed Simakan, Angelino, Amadou Haidara, Tyler Adams, Kevin Kampl, Hugo Novoa, Alexander Sorloth, Christopher NkunkuSandhausen vs RB Leipzig PredictionSandhausen finished 15th in the 2.Bundesliga last season. They have an experienced forward in the form of former Augsburg and Hertha Berlin attacker Alexander Esswein, and he will be key if they are to get a positive result against RB Leipzig.RB Leipzig, on the other hand, have invested heavily this summer. They have signed Mohamed Simakan, Josko Gvardiol, Andre Silva and Brian Brobbey, and also have a new manager at the helm in the form of Jesse Marsch.🗣️ @jessemarsch continues: "My first game in charge is a very important one straight away. I'm very pleased with how we trained in Saalfelden and with our preparations in Leipzig over the last few days." 🔴⚪ #RBLeipzig #SVSRBL pic.twitter.com/VR7uSJFG99— RB Leipzig English (@RBLeipzig_EN) August 5, 2021RB Leipzig will be the favourites to win this game.Prediction: Sandhausen 0-3 RB LeipzigAlso Read: Fabrizio Romano's Transfer Roundup: Chelsea pushing for major signing, updates on Lukaku and Kane's futures and more