#5 Shinsuke Nakamura losing the United States championship
Jeff Hardy looks more and more beat up every week. He should take it easy to recover from some of his injuries.
There's also a lot more left to explore with a Shinsuke Nakamura championship reign, and having him drop the title right now even if his opponent wasn't banged up would be foolish to begin with.
The US title has grown more interesting, especially with Randy Orton's return. What presence the Viper will have (if any, given his currently embattled status) is unknown, but it shouldn't do anything to change the proper result.