When, the St. Louis Cardinals travel to Canada for a series against the Toronto Blue Jays, they will be without two of their best players. Nolan Arenado and Paul Goldschmidt will not join the team because of current vaccine mandates. This makes the series even tougher for the Cardinals, who need to be at their best against the Blue Jays.Ben Fredrickson was the first to report that these two All-Stars will not make the trip north of the border.Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?22523#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?This led to a divisive reaction among St. Louis Cardinals fans. Since they want to win as many games as possible in order to make the playoffs, they want to see the stars play.Kendall@knavv22It makes me disappointed. Pretty selfish decision on their parts. Division is within reach and we’re without our two best hitters… ugh twitter.com/Ben_Fred/statu…Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?223#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?It makes me disappointed. Pretty selfish decision on their parts. Division is within reach and we’re without our two best hitters… ugh twitter.com/Ben_Fred/statu…Some were more forgiving of the two stars and were able to look past the effect this will have on the upcoming series.Jared Humphry🤟🏼@JHumphry25Proud of them tbh twitter.com/ben_fred/statu…Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?123#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?Proud of them tbh twitter.com/ben_fred/statu…Jeff Pickles@jeff_picklesWell this is disappointing for many reasons. twitter.com/ben_fred/statu…Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?22523#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?Well this is disappointing for many reasons. twitter.com/ben_fred/statu…Gas Mask Sports@GasMaskSportsThat's their choice. twitter.com/Ben_Fred/statu…Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?22523#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?That's their choice. twitter.com/Ben_Fred/statu…Foster@FosterThePrson@Ben_Fred talk about lack of awareness, extremely disappointed in these guys1@Ben_Fred talk about lack of awareness, extremely disappointed in these guysDebbie Egley@degley45I think it’s awesome that they are standing up for their principles! Bravo @NolanArenado28_ and @Paulgoldschmi44 twitter.com/ben_fred/statu…Ben Frederickson@Ben_Fred#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?22523#STLCards will be without Paul Goldschmidt and Nolan Arenado for games against Blue Jays in Toronto due to noncompliance with Canada's vaccination rules. Cards enter today's game against Reds 1.5 games behind Brewers in NL Central. Honest question: How does that news hit you?I think it’s awesome that they are standing up for their principles! Bravo @NolanArenado28_ and @Paulgoldschmi44 twitter.com/ben_fred/statu…Rich White@Creoboy65@Ben_Fred Another disappointment in a world full of it right now. The two players we can LEAST afford to miss three games are the two we lose. And going unvaccinated goes against everything I believe in so that hurts more than the three games lost but to each his own....5@Ben_Fred Another disappointment in a world full of it right now. The two players we can LEAST afford to miss three games are the two we lose. And going unvaccinated goes against everything I believe in so that hurts more than the three games lost but to each his own....Chris Callahan@tennisdudz22@Ben_Fred Wow what an unfair advantage Toronto has not having to play other teams best players at home.111@Ben_Fred Wow what an unfair advantage Toronto has not having to play other teams best players at home.mattjensen@_mattjensen@Ben_Fred I respect them both even more now!692@Ben_Fred I respect them both even more now!David Bill@dsbill@Ben_Fred I thought Nolan wanted to help the team win the division. He must be banking on them finishing more than 2 games ahead of the Brewers12@Ben_Fred I thought Nolan wanted to help the team win the division. He must be banking on them finishing more than 2 games ahead of the BrewersIt is important to note that the United States has a similar vaccine mandate as Canada. If there were any players on the Toronto Blue Jays who were unvaccinated, they would not be able to cross the border either.Can the St. Louis Cardinals beat the Toronto Blue Jays without Arenado and Goldschmidt?St Louis Cardinals v Toronto Blue JaysGoing into a series on the road against a team that is able to score in bunches without your top two offensive players is a tall order. The best option they have is to shut down the Blue Jays' explosive offense. This is a task that is far easier said than done.The Toronto Blue Jays put up a whopping 40 runs in their last series against the Boston Red Sox. That is not a typo. They are going into this series against the Cardinals with confidence and momentum.The St. Louis Cardinals are just 2.5 games behind the Milwaukee Brewers for the National League Central lead. This series up north could have been their opportunity to take that lead. Without Arenado and Goldschmidt, that seems impossible.This is an issue that many teams across the MLB have had to deal with. As long as both countries maintain their vaccine mandates, it will be an issue for any player who is unvaccinated.Fans just want to see their teams play at their best against the best opposition they can face. Missing out on seeing stars like Arenado and Goldschmidt perform is a tough break. It has fans concerned about how it will affect the team.