Yankees vs. Astros: Game 2, prediction, odds, injuries and picks

The New York Yankees face off against the Houston Astros on Saturday, for the second of three games taking place in the Bronx over the weekend. The hosts sit third in the AL East with a 61-55 record, while the visitors occupy the top spot in the AL West at 65-51.

Let's take a look at the odds and how the action might play out on Saturday.

Yankees vs Astros prediction

Taking the mound for the hosts is 2024 AL Rookie of the Year winner, Luis Gil, who only made his first appearance of the season last week against the Miami Marlins. Gil had a rough outing, taking the loss and coming away with a 13.5 ERA in the 7-3 defeat.

Luis Gil in action against the Miami Marlins - Source: Getty

Offensively, Aaron Judge, Cody Bellinger, Paul Goldschmidt and Giancarlo Stanton are the key players for the Bronx Bombers.

For the Astros, two-time All-Star Framber Valdez makes his latest start. Boasting an 11-5 record, along with a 2.83 ERA and 144 total strikeouts, the Dominican has once again been extremely reliable for his team this season.

At the plate, Jose Altuve, Jeremy Pena, Yainer Diaz and Jesus Sanchez are the main men for the visitors.

Having been much more consistent over the course of the season, and with an extremely reliable starter in Framber Valdez on the mound, the Astros should secure a win on Saturday, clinching the series in the process.

Prediction: New York Yankees 4, Houston Astros 5

Odds

Money Line: New York Yankees -109, Houston Astros -109

Run Line: New York +1.5 (-179), Houston -1.5 (+146)

Total Runs: Over 7.5 (-139), Under 7.5 (+114)

Injury report

Yankees injuries

Austin Slater: 10-day IL (Hamstring)
Jonathan Loaisiga: 15-day IL (Back)
Fernando Cruz: 15-day IL (Oblique)
Ryan Yarbrough: 15-day IL (Oblique)
Gerrit Cole: 60-day IL (Elbow)
Oswaldo Cabrera: 60-day IL (Ankle)
Clarke Schmidt: 60-day IL (Forearm)
Jake Cousins: 60-day IL (Elbow)

Astros injuries

Jake Meyers: 10-day IL (Calf)
Lance McCullers: 15-day IL (Finger)
Shawn Dubin: 15-day IL (Forearm)
Brandon Walter: 15-day IL (Elbow)
Ronel Blanco: 60-day IL (Elbow)
J.P. France: 60-day IL (Shoulder)
Zach Dezenzo: 60-day IL (Hand)
Cristian Javier: 60-day IL (Elbow)
Brendan Rodgers: 60-day IL (Oblique)
Isaac Paredes: 60-day IL (Hamstring)
Hayden Wesneski: 60-day IL (Elbow)
Yordan Alvarez: 60-day IL (Hand)
Luis Garcia: 60-day IL (Elbow)
Pedro Leon: 60-day IL (Knee)

Expert's picks

With the pitching matchup leaning in their favor, the Astros should be able to pick up a hard-fought win on Saturday.

Money Line: Houston Astros -109

Run Line: New York +1.5 (-179)

Total Runs: Over 7.5 (-139)

About the author

Raghav Mehta is a baseball journalist at Sportskeeda awaiting results for a Bachelor's in Journalism from Delhi University. He enjoys highlighting the key battles between players at different stages of the game and analyzing the decisive moments upon which they hinge.

One of Raghav's favorite moments, which underscores this, was the Shohei Ohtani vs. Mike Trout clash in the 2023 WBC, where two of baseball's best players faced off against each other in the 9th inning. With the score 3-2 to Japan, Shohei eventually got the strikeout, which was absolute cinema.

Raghav is a Baltimore Orioles fan and is enjoying watching such an exciting young team compete at the top in a very competitive division.

Raghav has loved watching sports for as long as he can remember and realized he was pretty decent at writing his thoughts down at around the age of 14. Combining the two meant he had something he would enjoy doing every day, and he had identified that well before going to college.

Aside from work, Raghav enjoys playing sports, working out and watching movies.

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Edited by John Maxwell

Yankees vs. Astros: Game 2, prediction, odds, injuries and picks - August 9, MLB 2025