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Right-back: Trent Alexander-Arnold (Liverpool)
Liverpool will be boosted by the return of their talismanic right-back, who's made a difference for them in big games like this on so many occasions.
Widely considered among the best-ever full-backs in the Premier League, the 23-year-old's crossing ability is second to none. He can switch play instantly and creates numerous chances for his teammates.
Centre-back: Joel Matip (Liverpool)
After back-to-back seasons riddled with injuries, Joel Matip has returned to his best form again. He's duly repaid the faith Jurgen Klopp has shown in him following a centre-back rotation and looks set to keep Joe Gomez on the sidelines for now
He's forged a stoic partnership with Virgil van Dijk at the heart of defense. Combining vision, strength and awareness, the Cameroonian has played a big role in their side having the best defensive record in the league.
Centre-back: Virgil van Dijk (Liverpool)
The big Dutchman, who also missed a chunk of last season with a horrific knee injury, has made an incredible recovery. He's returned to the side like he's never left, coming up big in all his appearances this season.
Known for his strength, leadership and uncanny aerial ability, Van Dijk is widely hailed as the best centre-back in the world. However, his reputation will be put to the test on Tuesday.
Left-back: Andrew Robertson (Liverpool)
Completing our all-Liverpool defense is Scottish ace Andrew Robertson, who's brought a new dimension to the side's attack on the left. He and Alexander-Arnold's partnership is arguably the best full-back pairing in the world.
The former Hull City defender is blessed with electric pace and incredible energy, whilst possessing a crossing ability that's just as good as his full-back friend.
