The Premier League features one of England's most exciting derbies this weekend as Manchester United take on arch-rivals Manchester City at Old Trafford on Saturday. The two Premier League giants have not been at their best this season and will want to win their city's bragging rights this weekend.Manchester United crashed out of the UEFA Champions League earlier this week and suffered a shocking 3-2 defeat to RB Leipzig. The Red Devils are currently in sixth place in the Premier League standings and have a point to prove going into this game.Manchester City have largely recovered from their slow start to the season but have plenty of work to do ahead of this game. Pep Guardiola's side is one point behind Manchester United at the moment and will want to move further up the table this weekend.All eyes on the weekend 🔴#MUFC #MUNMCI pic.twitter.com/9dIAZiPky1— Manchester United (@ManUtd) December 10, 2020Manchester United vs Manchester City Head-to-HeadManchester United have a predictably good historical record against Manchester City and have won 76 games out of a total of 182 official matches played between the two sides. Manchester City have managed only 54 victories against their local rivals and will want to cut the deficit this weekend.The previous game between the two teams earlier this year ended in a surprising 2-0 victory for Manchester United. Scott McTominay scored a goal on the day and will want to make an impact on the result this weekend.Manchester United form guide in the Premier League: W-W-W-W-LManchester City form guide in the Premier League: W-W-L-D-WAlso Read: FIFA Best Player Awards Power Rankings: November 2020Manchester United vs Manchester City Team NewsAnthony Martial might not feature in this gameManchester UnitedManchester United have a few concerns with fitness in their final third and might not be able to field Anthony Martial and Edinson Cavani against Manchester City this weekend. Mason Greenwood and Marcus Rashford are likely to lead the line for the Red Devils.Injured: NoneDoubtful: Anthony Martial, Edinson CavaniSuspended: NoneSergio Aguero scored for Manchester City this weekManchester CitySergio Aguero was eased back into action for Manchester City in the Champions League but is unlikely to play a part in this game. Eric Garcia is also carrying knocks and might not feature against Manchester United.Injured: NoneDoubtful: Eric Garcia, Sergio AgueroSuspended: NoneManchester United vs Manchester City Predicted XIManchester United Predicted XI (4-2-3-1): David de Gea; Alex Telles, Victor Lindelof, Harry Maguire, Aaron Wan-Bissaka; Fred, Scott McTominay; Juan Mata, Bruno Fernandes, Marcus Rashford; Mason Greenwood🔥 Man City x @fazeclan 🔥AVAILABLE NOW! 🛒 https://t.co/STUnh8Ltox🎮 #FaZeCity 🔷 #ManCity | https://t.co/axa0klD5re pic.twitter.com/3spocE5QMH— Manchester City (@ManCity) December 10, 2020Manchester City Predicted XI (4-3-3): Ederson Moraes; Joao Cancelo, Ruben Dias, John Stones, Kyle Walker; Rodri, Ilkay Gundogan, Kevin De Bruyne; Raheem Sterling, Riyad Mahrez, Gabriel JesusManchester United vs Manchester City PredictionManchester United often tend to bring their best selves to this derby and will have a point to prove after their exit from the Champions League. The Red Devils have been fairly inconsistent this season and will rely heavily on Bruno Fernandes to provide the creative impetus in this game.Manchester City depend on a talisman of their own and the indomitable Kevin De Bruyne will have to be at his best this weekend. Manchester City have found their feet in recent weeks and hold a slight upper hand in this fixture.Prediction: Manchester United 1-2 Manchester CityAlso Read: Premier League 2019/20: Team of the season