After overseeing five losses and as many defeats in ten Premier League encounters, Nuno Espirito Santo was relieved of his duties with Tottenham Hotspur earlier today. The Portuguese tactician, who previously managed Valencia and Wolverhampton Wanderers among other teams, came under immense scrutiny after Spurs' 3-0 home defeat to Manchester United.In the wake of the result, reports emerged that Nuno could lose his job, with Spurs chairman Daniel Levy growing frustrated with his side's brand of football and recent results in the Premier League. The Lilywhites confirmed in their official statement that Nuno and the rest of his coaching staff have left the club with immediate effect. The statement read:"The Club can today announce that Nuno Espírito Santo and his coaching staff, Ian Cathro, Rui Barbosa and Antonio Dias, have been relieved of their duties.Fabio Paratici, Managing Director, Football, said: "I know how much Nuno and his coaching staff wanted to succeed and I regret that we have had to take this decision.“Nuno is a true gentleman and will always be welcome here. We should like to thank him and his coaching staff and wish them well for the future.”A further coaching update will follow in due course."Tottenham looking to appoint serial winner Antonio Conte FC Internazionale Milano v Udinese Calcio - Serie AThe good news for Tottenham, though, is that former Chelsea manager Antonio Conte is the frontrunner to take over the reins after Nuno. The Italian has been without a job since leaving Inter Milan this summer and came close to joining the Lilywhites after Jose Mourinho's sacking. However, Tottenham failed to agree a deal with him and instead appointed Nuno, as Conte waited for the right job to come his way.Nearly two months later, the one-time Premier League winner could be set to return to England, with Fabrizio Romano reporting that negotiations are well underway between all parties involved. Only time will tell if Conte replaces Nuno at Tottenham, but football fans on social media have had their say in what has been a tumultuous few hours for the north London club. On that note, here are the best tweets and reactions to Nuno's sacking, Conte's arrival and a lot more.Michael Hamilton COYS 🇯🇲@NLAHamiltonNuno before the 1st International break and Nuno today. 👀 Poor guy9:55 PM · Oct 31, 202124819Nuno before the 1st International break and Nuno today. 👀 Poor guy https://t.co/hPI1FMp1soMatt Law@Matt_Law_DTMy information is that Nuno remains on the brink of the sack tonight after a day of talks regarding his Tottenham future. Expectation remains a change is likely to be made #thfc twitter.com/TeleFootball/s…Telegraph Football@TeleFootballExclusive by @Matt_Law_DT: Nuno Espirito Santo on the brink of sack at Tottenham following urgent talks today and Daniel Levy furious after Man Utd capitulation telegraph.co.uk/football/2021/… #THFC #COYS03:45 AM · Nov 1, 20211863186Exclusive by @Matt_Law_DT: Nuno Espirito Santo on the brink of sack at Tottenham following urgent talks today and Daniel Levy furious after Man Utd capitulation telegraph.co.uk/football/2021/… #THFC #COYSMy information is that Nuno remains on the brink of the sack tonight after a day of talks regarding his Tottenham future. Expectation remains a change is likely to be made #thfc twitter.com/TeleFootball/s…Patrick Timmons@PatrickTimmons1It may have been brief, but thanks for the memories, Nuno.3:26 PM · Nov 1, 20212416219It may have been brief, but thanks for the memories, Nuno. https://t.co/iU17zjAVSdSquawka Football@SquawkaNuno Espírito Santo is the first manager to win the first three games of a Premier League campaign and then be sacked in the same season since Roberto Di Matteo at Chelsea in 2012/13. twitter.com/SquawkaNews/st…Squawka News@SquawkaNews◉ 30th June: Spurs appoint Nuno Espírito Santo as head coach◉ 10th September: Nuno Espírito Santo is named Manager of the Month for August ◉ 1st November: Nuno Espírito Santo is sackedA rollercoaster ride. 🎢3:51 PM · Nov 1, 202112849◉ 30th June: Spurs appoint Nuno Espírito Santo as head coach◉ 10th September: Nuno Espírito Santo is named Manager of the Month for August ◉ 1st November: Nuno Espírito Santo is sackedA rollercoaster ride. 🎢 https://t.co/XgmQPHGSAqNuno Espírito Santo is the first manager to win the first three games of a Premier League campaign and then be sacked in the same season since Roberto Di Matteo at Chelsea in 2012/13. twitter.com/SquawkaNews/st…yoli@yolanielinuno showing up to training today7:30 PM · Oct 31, 20214600349nuno showing up to training today https://t.co/qDDgF7iP4sAU@_23auThe fans booing Nuno for talking Lucas Moura off was my highlight of the game01:08 AM · Oct 31, 20211985211The fans booing Nuno for talking Lucas Moura off was my highlight of the game https://t.co/TqnlHVWdq1Fabrizio Romano@FabrizioRomanoAntonio Conte is ready to accept Tottenham proposal. Talks underway and understood to be ‘at final stages’ - salary and long term contract discussed but he seems convinced to say ‘yes’. ⚪️🇮🇹 #THFCNegotiations to continue in the next few hours in order to complete the agreement.3:49 PM · Nov 1, 2021133332392Antonio Conte is ready to accept Tottenham proposal. Talks underway and understood to be ‘at final stages’ - salary and long term contract discussed but he seems convinced to say ‘yes’. ⚪️🇮🇹 #THFCNegotiations to continue in the next few hours in order to complete the agreement. https://t.co/quih3onc7zFabrizio Romano@FabrizioRomanoTottenham board feeling ‘more than confident’ to convince Antonio Conte and appoint him as new manager to replace Nuno. Talks progressing right now with Conte’s camp. ⚪️🇮🇹 #THFCHe’s asking an important plan for next transfers window and long-term contract. Paratici is on it.3:33 PM · Nov 1, 2021139031838Tottenham board feeling ‘more than confident’ to convince Antonio Conte and appoint him as new manager to replace Nuno. Talks progressing right now with Conte’s camp. ⚪️🇮🇹 #THFCHe’s asking an important plan for next transfers window and long-term contract. Paratici is on it.hash@hashim0307Solskjær knew he was closed to being replaced by Conte, so he destroyed Tottenham in order to get Nuno sacked and Conte to replace him. Fewer candidates for the United job. Solskjær safe. The man is actually a genius.3:42 PM · Nov 1, 202116045Solskjær knew he was closed to being replaced by Conte, so he destroyed Tottenham in order to get Nuno sacked and Conte to replace him. Fewer candidates for the United job. Solskjær safe. The man is actually a genius.Melissa Reddy@MelissaReddy_Told part of the lack of hesitation in axing Nuno (beyond the dire football that has dispirited fans) and pushing heavily for Antonio Conte is Tottenham not wanting to lose out on his brilliance to another club - especially given he has been very open to taking over at Man Utd3:53 PM · Nov 1, 20212113Told part of the lack of hesitation in axing Nuno (beyond the dire football that has dispirited fans) and pushing heavily for Antonio Conte is Tottenham not wanting to lose out on his brilliance to another club - especially given he has been very open to taking over at Man UtdRamo♟@RamoBallNuno uses recommended subs on FIFA11:32 PM · Oct 30, 20213822295Nuno uses recommended subs on FIFA⚡™️@ANlUTDSpurs fans boo Nuno and the stadium gets toxic when they're on better form than us and now Spurs are on the verge of sacking Nuno and getting Conte. Meanwhile our fans sing Ole's name 6 days after we lose 5-0 at home to the scousers.04:45 AM · Nov 1, 20212427278Spurs fans boo Nuno and the stadium gets toxic when they're on better form than us and now Spurs are on the verge of sacking Nuno and getting Conte. Meanwhile our fans sing Ole's name 6 days after we lose 5-0 at home to the scousers.ᴴ@HaroIdCuntWhy isn't Gary Glazer Neville on Sky begging for Nuno to be given 3 years, £500m and blaming Harry Kane for not scoring?#OleOut7:00 PM · Oct 31, 20213626467Why isn't Gary Glazer Neville on Sky begging for Nuno to be given 3 years, £500m and blaming Harry Kane for not scoring?#OleOutZach Lowy@ZachLowyNuno Espírito Santo is out of his depth and will pay the price with an early dismissal, but the root of Tottenham’s problems is Daniel Levy.Instead of selling a disinterested Harry Kane and improving a dire squad, he kept him to boost his own ego and undercut Nuno as a result.6:58 PM · Oct 31, 20212025295Nuno Espírito Santo is out of his depth and will pay the price with an early dismissal, but the root of Tottenham’s problems is Daniel Levy.Instead of selling a disinterested Harry Kane and improving a dire squad, he kept him to boost his own ego and undercut Nuno as a result.Alasdair Gold@AlasdairGoldI do feel sorry for Nuno as he's clearly a good bloke and I enjoyed trying to get him to talk about, well anything. However, he was clearly the wrong man at the wrong time. I think I said back when talks were taking place with him that he just didn't fit what Spurs needed.3:45 PM · Nov 1, 2021143099I do feel sorry for Nuno as he's clearly a good bloke and I enjoyed trying to get him to talk about, well anything. However, he was clearly the wrong man at the wrong time. I think I said back when talks were taking place with him that he just didn't fit what Spurs needed.S@9squeezePogba fans thought Conte was gonna come save their boy3:56 PM · Nov 1, 20218715Pogba fans thought Conte was gonna come save their boy https://t.co/7JcYuhO69QFootball Daily@footballdaily🗣 "If someone doesn't have a good attitude or behaviour, I prefer to kill him."Antonio Conte speaking about how he deals with bad attitudes in the dressing room 👀3:43 PM · Nov 1, 202141257🗣 "If someone doesn't have a good attitude or behaviour, I prefer to kill him."Antonio Conte speaking about how he deals with bad attitudes in the dressing room 👀https://t.co/gvLvF7AM94LP@thfclp__Saw a ton of camera crew outside. Thought it was for Conte, turns out it’s just Dele doing a boohooMAN photoshoot. twitter.com/thfclp__/statu…LP@thfclp__I’m driving past the Tottenham training ground tomorrow I’ll try and get some #exclusives🚨3:42 PM · Nov 1, 202137823I’m driving past the Tottenham training ground tomorrow I’ll try and get some #exclusives🚨Saw a ton of camera crew outside. Thought it was for Conte, turns out it’s just Dele doing a boohooMAN photoshoot. twitter.com/thfclp__/statu…Squawka Football@SquawkaAs Chelsea manager, Antonio Conte became the first to:◉ Win 30 games in a single Premier League season◉ Complete a league double against a side managed by Pep Guardiola◉ Beat José Mourinho in an English domestic cup final That 3-4-3. 🤤twitter.com/i/events/13973…3:35 PM · Nov 1, 202136169As Chelsea manager, Antonio Conte became the first to:◉ Win 30 games in a single Premier League season◉ Complete a league double against a side managed by Pep Guardiola◉ Beat José Mourinho in an English domestic cup final That 3-4-3. 🤤twitter.com/i/events/13973…CFCDaily@CFCDailyAVB, Mourinho & potentially Conte all at Chelsea & Spurs in the last 10 years 😂3:51 PM · Nov 1, 202164857AVB, Mourinho & potentially Conte all at Chelsea & Spurs in the last 10 years 😂Lyés@WholeLottaLyesI think Conte’s team is pushing this story to pressure Man United. I don’t think Conte takes the Spurs job without being 1000% certain United are not firing Ole this season.04:42 AM · Nov 1, 2021186898I think Conte’s team is pushing this story to pressure Man United. I don’t think Conte takes the Spurs job without being 1000% certain United are not firing Ole this season.R8 🚜🌾@NabyllionaireConte saw Doherty and said I'll take the job3:48 PM · Nov 1, 2021803Conte saw Doherty and said I'll take the jobAlso Read: "It would be extraordinary" - PSG superstar Lionel Messi doesn't think he is the favorite for the 2021 Ballon d'Or