The UEFA Champions League is back with an exciting fixture this week as Barcelona host Paris Saint-Germain in a round-of-16 clash at the Parc des Princes on Wednesday. Paris Saint-Germain thrashed Barcelona in the first leg but cannot afford to be overconfident going into this game.Barcelona have been a resurgent force this month and have enjoyed an excellent week both on and off the pitch. The Catalans stunned Sevilla with a brilliant comeback in the Copa del Rey last week and will need to pull off a similar result in this match.Paris Saint-Germain have managed to recover from a slow start to their season and will be intent on winning a treble in the coming months. The French champions have kept clean sheets in their last three games and will be confident ahead of this fixture.💪🟦🟥 𝘉𝘰𝘯 𝘥𝘪𝘢 ! Joan Laporta's Monday morning visit to the Ciutat Esportiva Joan Gamper pic.twitter.com/H0957O6Q4S— FC Barcelona (@FCBarcelona) March 8, 2021Paris Saint-Germain vs Barcelona Head-to-HeadBarcelona have a marginal advantage over Paris Saint-Germain as far as the head-to-head record is concerned and have won four out of nine matches played between the two teams. Paris Saint-Germain have managed three victories against Barcelona and have troubled their Catalan opponents in recent years.The first leg took place last month and ended in an emphatic 4-1 victory for Paris Saint-Germain at the Camp Nou. Kylian Mbappe scored a sensational hat-trick on the day and will want to make his mark on this fixture.Paris Saint-Germain form guide: W-W-W-L-WBarcelona form guide: W-W-W-W-DAlso Read: Atletico Madrid 1-1 Real Madrid: Player Ratings as Benzema and Suarez exchange blows in intriguing derby draw | La Liga 2020-21Paris Saint-Germain vs Barcelona Team NewsParis Saint-Germain have an excellent squadParis Saint-GermainMoise Kean has tested positive for the coronavirus and has been ruled out of the game this weekend. Neymar has made commendable progress with his recovery but is unlikely to be risked against his former side this week.Injured: Moise Kean, Juan BernatDoubtful: Neymar, Colin DagbaSuspended: NoneBarcelona have a depleted squadBarcelonaGerard Pique's heroics against Sevilla in the Copa del Rey came at a cost as the veteran defender has been sidelined for this game. Barcelona's 3-5-2 formation has yielded good results in recent weeks and Samuel Umtiti is likely to partner Oscar Mingueza and Clement Lenglet to form the Catalans' back-line.Philippe Coutinho, Ansu Fati, Sergi Roberto, and Ronald Araujo are also injured and remain unavailable this week. Ousmane Dembele was benched against Osasuna and is likely to start this game.Injured: Philippe Coutinho, Ansu Fati, Sergi Roberto, Ronald Araujo, Gerard PiqueDoubtful: NoneSuspended: NoneParis Saint-Germain vs Barcelona Predicted XIParis Saint-Germain Predicted XI (4-2-3-1): Keylor Navas; Layvin Kurzawa, Presnel Kimpembe, Marquinhos, Alessandro Florenzi; Idrissa Gueye, Leandro Paredes; Marco Verratti, Angel Di Maria, Kylian Mbappe; Mauro Icardi💜💪 Make the symbol and join the movement!#WomensDay | #WeAreAllDifferent8M pic.twitter.com/lBIAFCb0Zr— FC Barcelona (@FCBarcelona) March 8, 2021Barcelona Predicted XI (3-5-2): Marc-Andre ter Stegen; Clement Lenglet, Samuel Umtiti, Oscar Mingueza; Jordi Alba, Sergino Dest, Sergio Busquets, Frenkie de Jong, Pedri; Ousmane Dembele, Lionel MessiParis Saint-Germain vs Barcelona PredictionBarcelona have been on cloud nine this week after waves of optimism swept through the club following a positive election result and a series of important victories. The Catalans have a mountain to climb in France on Wednesday and are likely to adopt an aggressive approach to this encounter.Paris Saint-Germain have four away goals in this fixture and hold all the cards ahead of this week's game. Barcelona are perfectly capable of winning this match but are unlikely to overcome what has become a massive first-leg deficit.Prediction: Paris Saint-Germain 2-3 BarcelonaAlso Read: Osasuna 0-2 Barcelona: Player Ratings as Catalans make title statement ahead of Madrid derby | La Liga 2020-21