Steelers vs Colts: Who Will Win? Betting Prediction, Odds, Lines, and Picks for NFL Games Today - November 28

The Pittsburgh Steelers and the Indianapolis Colts will face off at Lucas Oil Stadium in Indianapolis, Indiana, on Monday (November 28) night to wrap up the Week 12 NFL slate.

The Steelers are last in the AFC North with a 3-7 record and are coming off a 37-30 home loss against the Cincinnati Bengals last Sunday. The Colts, meanwhile, are in second place in the AFC South with a 4-6-1 record and are coming off a 17-16 home defeat against the Philadelphia Eagles on Sunday.

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Pittsburgh Steelers vs Indianapolis Colts Match Details

Fixture: Pittsburgh Steelers vs Indianapolis Colts

Date & Time: Monday, November 28, 2022; 8:15 pm EST

Venue: Lucas Oil Stadium, Indianapolis, Indiana

Pittsburgh Steelers vs Indianapolis Colts Betting Odds

Team	Spread	Moneyline	Over/Under
Steelers	+2.5 (-105)	+120	Over 39.5 (-107)
Colts	-2.5 (-110)	-140	Under 39.5 (-107)

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Pittsburgh Steelers vs Indianapolis Colts Best Picks

Kenny Pickett has shown a bit of improvement recently, so 216+ passing yards seem plausible.

In the last four games, Pickett has averaged 228 passing yards per outing. The Colts defense has been doing well in terms of limiting passing yards, giving up just 209.9 yards per game. However, Indianapolis' defense is dealing with a bunch of injuries as well, so take the over on Kenny Pickett passing yards.

Kenny Pickett Over 215.5 Passing Yards (-110)

Michael Pittman is the Colts' top wide receiver but has not been able to get going of late, as coach Jeff Saturday seems to be liking the running game a lot more.

Pittman is averaging just 50 receiving yards per game in his last three outings. The Steelers' secondary should limit the amount of production Pittman has in this game.

Michael Pittman Under 65.5 Receiving Yards (-110)

Pittsburgh Steelers vs Indianapolis Colts Prediction

This is expected to be a low-scoring game, so don't expect too much. In their last three games, Pittsburgh has averaged 21 points, while Indianapolis has scored 14.7 points per outing.

Kenny Pickett is improving, and Mike Tomlin is likely going to coach circles around Jeff Saturday. The Steelers are 5-1 ATS in their last six games against the Colts, so go with the Pittsburgh Steelers to cover the spread.