5 Likely opponents for WWE Universal Champion Roman Reigns after the 2021 Royal Rumble 

#1 Rey Mysterio may have one last run left in him and it may involve a Roman Reigns feud and a Universal Championship program

Roman Reigns vs. Rey Mysterio is just a feud that makes sense if you consider the size difference between both men and how good the quality of matches between both performers will be. Check out Seth Rollins breaking character in an SK Wrestling exclusive, speaking about how much he admires Rey Mysterio as a colleague.

.@WWERollins looks back at the legacy of @reymysterio and talks about working with @DomMysterio35.Watch #WWE ‘Birth of a Champion’ every Monday, Wednesday, Friday, and Sunday at 8 PM IST only on SONY TEN 1 (English) & SONY TEN 3 (Hindi) channels.@SonySportsIndia @WWEIndia pic.twitter.com/4zQQHkqhzB

— SK Wrestling (@SKWrestling_) September 23, 2020

Sure, it may not be a WrestleMania worthy match yet, but to be fair, if WWE needs a feud to kill time until then, Rey Mysterio vs. Roman Reigns is the way to go. Even if Mysterio comes up short, it will still be a step up from everything he's doing right now.

"I called Rey and I asked him, 'Rey, is there a chance that I could wear your wristbands for the match?' And he said, 'No. I'm going to send over the entire gear." - @EscobarWWE on the night he paid homage to @reymysterio and Eddie Guerrero. @SKWrestling_ https://t.co/oAHB5sGbTw

— Rick Ucchino (@RickUcchino) January 27, 2021

In fact, it does seem like Rey Mysterio has done nothing of significance since his feud with Seth Rollins.

Roman Reigns working with someone and effectively even bullying so much smaller will help him garner even more heel heat than he currently has.