Padres vs. Phillies: Game 2 prediction, odds, injuries, and picks

It’s a classic pitchers’ showdown on tap in Philadelphia as the Phillies and Padres clash in Game 2 of their midseason series on Tuesday. Fresh off a dominant shutout in the opener, the Phillies look to keep their home dominance alive behind the steady left arm of Cristopher Sanchez.

San Diego turns to Nick Pivetta, who’s been on a tear and quietly ranks among the NL’s toughest pitchers to square up this season. With both teams chasing crucial midseason wins and star names like Bryce Harper back in the mix, Tuesday feels like one of those gritty, edge-of-your-seat showdowns under the lights in Philly.

Pitcher & Hitter Matchups

Starting Pitchers

Nick Pivetta (RHP, Padres): At 8–2 with a 3.36 ERA and 101 strikeouts in 97 innings, Pivetta has been San Diego’s most reliable starter. He’s coming off a 10-strikeout shutout performance against Washington and owns a sharp 2.98 ERA in six road starts this season.

Cristopher Sánchez (LHP, Phillies): Sánchez enters at 6–2 with a 2.79 ERA and 103 strikeouts over 100.2 innings. The lefty has anchored the Phillies’ rotation, with the team going 11–3 in his starts, while holding opponents to a .224 average at Citizens Bank Park.

Key Hitters to Watch

Phillies:

Trea Turner: .295 AVG, 17 doubles, 20 steals - the engine at the top of the order.

Bryce Harper: Back from a 22-game IL stint, batting .256 with a .370 OBP and 9 homers.

Nick Castellanos & Kyle Schwarber: Both power threats with a combined 35 HRs this season.

Padres:

Manny Machado: .293 AVG, 13 HR, 47 RBI - remains the team’s offensive leader.

Fernando Tatis Jr.: 15 HR, 17 steals, dynamic at the plate and in the field.

Luis Arraez: .286 AVG, 4 HR - contact machine, tough out against lefties.

Projected Starting Lineups

San Diego Padres (Away Team):

DH Luis Arraez
3B Manny Machado
CF Jackson Merrill
RF Fernando Tatis Jr.
SS Xander Bogaerts
LF Gavin Sheets
2B Jose Iglesias
1B Jake Cronenworth
C Martin Maldonado
SP: Nick Pivetta

Philadelphia Phillies (Home Team):

SS Trea Turner
DH Kyle Schwarber
1B Bryce Harper
3B Alec Bohm
RF Nick Castellanos
LF Max Kepler
C J.T. Realmuto
2B Bryson Stott
CF Brandon Marsh
SP: Cristopher Sanchez

Injury Report

Phillies:

Aaron Nola (rib fracture): 60-day IL, out through mid-July

Orion Kerkering (elbow): 15-day IL

Bryce Harper: Recently activated, returned to the starting lineup Monday

Padres:

Yu Darvish (elbow), Joe Musgrove (elbow), Jhony Brito (shoulder): all on 60-day IL

Michael King (shoulder) and Ryan Bergert (forearm): on 15-day IL

Matt Waldron struggled in his Monday start, leaving the bullpen slightly taxed

Updated Odds:

Phillies Runline (–1.5): +128
Phillies Moneyline: –171
Padres Runline (+1.5): –156
Padres Moneyline: +140
Total – Over 8: –118
Total – Under 8: –103

Expert Prediction & Best Bets

Final Score Prediction: Phillies 4, Padres 3

Best Bets:

Phillies Moneyline (–171) - Sanchez at home with Bryce Harper back tips the edge.
Padres +1.5 Runline (–156) - Pivetta can keep it tight, even in a loss.
Lean: Under 8 (–103) - With two in-form starters, this projects as a pitcher’s duel.

Value Parlay: Phillies ML + Under 8 pays at a solid +200 range, worth a small-unit play.

About the author

Shubham Soni is a dedicated baseball journalist at Sportkeeda with a deep passion for Major League Baseball. Specializing in player profiles, in-depth analysis, and trade updates, He provides readers with expert insights and strategic advice to enhance their fantasy sports experience. With a keen focus on player performances, game previews, and betting trends.

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Edited by nagpaltusharn25

Padres vs. Phillies: Game 2 prediction, odds, injuries, and picks - July 1, 2025