Yankees vs Angels: Game 1 prediction, odds, injuries, and picks

Having won their last series at Coors Field, the New York Yankees head to Anaheim on Monday to take on the Los Angeles Angels, opening up another three-game series.

The Bronx Bombers - currently 32-20 - sit top of the AL East while the Angels find themselves fourth in the AL West with a 25-27 record.

Let's examine the odds for the matchup and consider how the action might unfold on the field.

Yankees vs. Angels prediction

Ryan Yarbrough will take the mound for New York. So far, the lefty has enjoyed a strong season, boasting a 1-0 record, a 3.38 ERA, and 28 strikeouts. In his most recent appearance, Yarbrough gave up only one earned run in five innings against the Texas Rangers, striking out eight.

Ryan Yarbrough in action during an MLB game. (Credits: Getty)

Offensively, the formidable trio of Aaron Judge, Paul Goldschmidt and Cody Bellinger are all swinging extremely hot bats for the visitors.

Righty Jack Kochanowicz makes his eleventh start of the season for the Angels. So far, the youngster has appeared to struggle, with a 3-5 record, along with a 5.03 ERA and 35 total strikeouts. In his recent appearance, Kochanowicz gave up four earned runs in four innings against the Athletics in Sacramento.

At the plate, Taylor Ward, Zach Neto, Nolan Schanuel and Logan O'Hoppe have led the way for the Angels.

Having won their last two games, the Bronx Bombers' superior quality should power them to a third win on the bounce here.

Prediction: New York Yankees 6, Los Angeles Angels 3

Yankees vs. Angels Odds

Money Line: New York Yankees -167, Los Angeles Angels +141

Run Line: New York -1.5 (-118), Angels +1.5 (-112)

Total Runs: Over 8.5 (-156), Under 8.5 (+117)

Yankees vs. Angels Injury report

Yankees injuries:

Oswaldo Cabrera: 10-day IL (Ankle)

Jazz Chisholm Jr.: 10-day IL (Side

Fernando Cruz: 15-day IL (Shoulder)

Marcus Stroman: 15-day IL (Knee)

Gerrit Cole: 60-day IL (Elbow)

Luis Gil: 60-day IL (Back)

Giancarlo Stanton: 60-day IL (Elbow)

JT Brubaker: 60-day IL (Ribs)

Jake Cousins: 60-day IL (Elbow)

Angels injuries:

Mike Trout: 10-day IL (Knee)

Gustavo Campero: 10-day IL (Ankle)

Jose Fermin: 15-day IL (Elbow)

Garrett McDaniels: 15-day IL (Bicep)

Anthony Rendón: 60-day IL (Hip)

Robert Stephenson: 60-day IL (Elbow)

Ben Joyce: 60-day IL (Shoulder)

Yankees vs. Angels Expert's picks

Looking at the pitching matchup and both team's records for the season, it is tough to bet against the Bronx Bombers registering a commanding victory.

Money Line: New York Yankees -167

Run Line: New York -1.5 (-118)

Total Runs: Over 8.5 (-156)

About the author

Raghav Mehta is a baseball journalist at Sportskeeda awaiting results for a Bachelor's in Journalism from Delhi University. He enjoys highlighting the key battles between players at different stages of the game and analyzing the decisive moments upon which they hinge.

One of Raghav's favorite moments, which underscores this, was the Shohei Ohtani vs. Mike Trout clash in the 2023 WBC, where two of baseball's best players faced off against each other in the 9th inning. With the score 3-2 to Japan, Shohei eventually got the strikeout, which was absolute cinema.

Raghav is a Baltimore Orioles fan and is enjoying watching such an exciting young team compete at the top in a very competitive division.

Raghav has loved watching sports for as long as he can remember and realized he was pretty decent at writing his thoughts down at around the age of 14. Combining the two meant he had something he would enjoy doing every day, and he had identified that well before going to college.

Aside from work, Raghav enjoys playing sports, working out and watching movies.

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Edited by William Paul

Yankees vs Angels: Game 1 prediction, odds, injuries, and picks - May 26, 2025