Orioles vs Athletics: Game 2 prediction, odds, injuries and picks - June 7, 2025

The Baltimore Orioles will take on the Athletics in the second of three games at Sutter Health Park, Sacramento, on Saturday.

Both teams are having tough seasons. The Orioles are at the bottom of the AL East with a 25-37 record, while the Athletics are in last place in the AL West at 25-40.

Here's a look at the odds for Saturday's fixture, and how the action might play out on the field.

Orioles vs Athletics prediction

Taking the mound for Baltimore is veteran Charlie Morton, who has struggled with consistency. He has a 2-7 record, along with a 6.20 ERA and 52 strikeouts.

Charlie Morton in action - Source: Getty

With the bat, Ryan O'Hearn, Jackson Holliday and Gunnar Henderson have looked good for the visitors.

For the hosts, righty Luis Severino gets the starting nod. On paper, Severino has fared better than his counterpart, with a 1-5 record, along with a 4.54 ERA and 55 strikeouts.

Offensively, Jacob Wilson, Brent Rooker, Tyler Soderstrom and Lawrence Butler are doing much of the heavy lifting for the A's.

Having won two games in a row, the Athletics should find a way to make it three consecutive on Saturday and clinch the series.

Prediction: Athletics 6, Baltimore Orioles 5

Odds

Money line: Baltimore Orioles -125, Athletics +107

Run line: Baltimore +1.5 (-256), Athletics -1.5 (+185)

Total runs: Over 8.5 (-238), Under 8.5 (+175)

Injury report

Baltimore injuries:

Ryan Mountcastle: 10-day IL (Hamstring)

Jordan Westburg: 10-day IL (Hamstring)

Tyler O’Neill: 10-day IL (Shoulder)

Cedric Mullins: 10-day IL (Hamstring)

Gary Sánchez: 10-day IL (Wrist)

Albert Suarez: 60-day IL (Shoulder)

Kyle Bradish: 60-day IL (Elbow)

Grayson Rodriguez: 60-day IL (Elbow)

Tyler Wells: 60-day IL (Elbow)

Cody Poteet: 60-day IL (Shoulder)

Athletics injuries:

Miguel Andujar: 10-day IL (Oblique)

Gio Urshela: 10-day IL (Hamstring)

Shea Langeliers: 10-day IL (Oblique)

Gunnar Hoglund: 15-day IL (Hip)

Nick Kurtz: 10-day IL (Hip)

Luis Medina: 60-day IL (Elbow)

J.T. Ginn: 15-day IL (Quad)

Jose Leclerc: 60-day IL (Shoulder)

Ken Waldichuk: 60-day IL (Elbow)

Zack Gelof: 60-day IL (Hand)

Brady Basso: 60-day IL (Shoulder)

Denzel Clarke: day-to-day (Shoulder)

Expert's picks

Playing at home, and with the pitching matchup leaning slightly in their favor, the A's should be able to get to Charlie Morton early and come out on top.

Money Line: Athletics +107

Run Line: Baltimore +1.5 (-256)

Total Runs: Over 8.5 (-238)