Novak Djokovic and Ashleigh Barty projected top seeds for 2021 US Open

World No. 1s Novak Djokovic and Ashleigh Barty are the projected top seeds for the 2021 US Open, which will get underway in New York on Monday.

Canadian Open champion Daniil Medvedev, French Open finalist Stefanos Tsitsipas, and Cincinnati Masters champion Alexander Zverev round out the projected top four seeds on the men's side.

With the withdrawals of Rafael Nadal and Dominic Thiem, Cincinnati runner-up Andrey Rublev should be bumped up to the fifth seed, followed by Wimbledon finalist Matteo Berrettini, Canada's Denis Shapovalov and Norway's Casper Ruud.

John Isner, the top-ranked American in this year's draw, is the projected No. 19 seed while Reilly Opelka is No. 22. Former champion Andy Murray will be unseeded.

Below is a list of the projected seedings:

1. Novak Djokovic
2. Daniil Medvedev
3. Stefanos Tsitsipas
4. Alexander Zverev
5. Andrey Rublev
6. Matteo Berrettini
7. Denis Shapovalov
8. Casper Ruud
9. Pablo Carreno Busta
10. Hubert Hurkacz
11. Diego Schwartzman
12. Felix Auger-Aliassime
13. Jannik Sinner
14. Alex de Minaur
15. Grigor Dimitrov
16. Cristian Garin
17. Gael Monfils
18. Roberto Bautista Agut
19. John Isner
20. Lorenzo Sonego
21. Aslan Karatsev
22. Reilly Opelka
23. Ugo Humbert
24. Daniel Evans
25. Karen Khachanov
26. Cameron Norrie
27. David Goffin
28. Fabio Fognini
29. Alejandro Davidovich Fokina
30. Marin Cilic
31. Alexander Bublik
32. Filip Krajinovic

Barty projected top seed in US Open women's draw

Ashleigh Barty at the 2019 US Open

Having won her second Grand Slam title at Wimbledon, Australia's Ashleigh Barty enters the US Open as the firm favorite. The 25-year-old lifted the Western & Southern Open title in Cincinnati on Sunday and will be aiming to win her first hardcourt Major in New York.

Aryna Sabalenka, two-time defending champion Naomi Osaka and Wimbledon finalist Karolina Pliskova round out the projected top four seeds. Elina Svitolina, Bianca Andreescu, Iga Swiatek, and Barbora Krejcikova are expected to complete the top eight.

Six-time US Open champion Serena Williams announced her withdrawal from the tournament on Wednesday due to a torn hamstring. The American will have to wait until next year to resume her quest for a record-equalling 24th Grand Slam title.

Venus Williams, a two-time winner at Flushing Meadows, joined younger sister Serena in pulling out of the Grand Slam with a leg injury.

Below is a list of the projected seedings:

1. Ashleigh Barty
2. Aryna Sabalenka
3. Naomi Osaka
4. Karolina Pliskova
5. Elina Svitolina
6. Bianca Andreescu
7. Iga Swiatek
8. Barbora Krejcikova
9. Garbiñe Muguruza
10. Petra Kvitova
11. Belinda Bencic
12. Simona Halep
13. Jennifer Brady
14. Anastasia Pavlyuchenkova
15. Elise Mertens
16. Angelique Kerber
17. Maria Sakkari
18. Victoria Azarenka
19. Elena Rybakina
20. Ons Jabeur
21. Cori Gauff
22. Karolina Muchova
23. Jessica Pegula
24. Paula Badosa
25. Daria Kasatkina
26. Danielle Collins
27. Jelena Ostapenko
28. Anett Kontaveit
29. Veronika Kudermetova
30. Petra Martic
31. Yulia Putintseva
32. Ekaterina Alexandrova