Saccomanno was a contestant in the sixth season of WWE Tough Enough in 2015. She came second in the show and adopted the name, Mandy Rose. After signing a five-year deal with WWE, she made her NXT debut in 2016. She worked in NXT for over a year before her main roster debut.
Absolution and Rivalry with Sonya Deville (2017-2020)
Rose arrived on the main roster and teamed up with Paige and Sonya Deville to form Absolution. They dissolved the stable in less than a month due to Paige's life-threatening injury. However, Rose and Deville stayed as a team. She took part in the inaugural Royal Rumble and WrestleMania Women's Battle Royale and lost. After Mania, she was drafted to SmackDown.
On SmackDown, she began a rivalry with Naomi to win over her husband, Jimmy Uso. The feud ended when the two eliminated each other at Royal Rumble. Rose and Deville took part at Elimination Chamber 2019 for the WWE Women's Tag Team Championship and lost to the winners. After Mania, they chased for the title for over six months. In 2019, she entered into a storyline with Otis.
The team exploded before WrestleMania when she found out Deville was helping Dolph Ziggler to take out Otis. At WrestleMania 36, she aided Otis as he defeated Dolph Ziggler. The feud between Rose and Deville continued and concluded at SummerSlam in a Loser Leaves WWE match, which Rose won. Rose was drafted to RAW and formed a team with Dana Brooke, which lasted for over a year.
NXT Champion (2021-Present)
In July, they sent Rose to NXT. The following month, she created a stable called Toxic Attraction with Gigi Dolin and Jacy Jayne. At Halloween Havoc 2021, the trio captured the NXT Championship and NXT Women's Tag Team Championship.
At WarGames, Team Dakota and Toxic Attraction lost to Team González. In 2022, Rose began feuding with Cora Jade. At Stand and Deliver, Rose retained her title against Cora Jade, Io Shirai, and Kay Lee Ray.
She would go on to defend her title against various competitors over the next months. At Worlds Collide 2022, she defeated Blair Davenport and NXT UK Women's Championship Meiko Satamura to unify the two titles while the NXT UK brand went onto a brief hiatus.