West Indies' Chris Gayle has hit 63 sixes in all of the T20 World Cups which makes him the player leading the chart for the most sixes hit in T20 World Cups.
| Pos | Player | Team | Matches | Runs | 4s | 6s | Avg | SR |
| 1 | CH Gayle | West Indies | 33 | 965 | 78 | 63 | 34.46 | 142.75 |
| 2 | RG Sharma | India | 37 | 921 | 85 | 35 | 35.42 | 129.35 |
| 3 | Yuvraj Singh | India | 31 | 593 | 38 | 33 | 23.72 | 128.91 |
| 4 | SR Watson | Australia | 24 | 537 | 41 | 31 | 28.26 | 140.94 |
| 5 | DA Warner | Australia | 33 | 781 | 81 | 31 | 25.19 | 133.04 |
| 6 | AB de Villiers | South Africa | 30 | 717 | 51 | 30 | 29.87 | 143.4 |
| 7 | JC Buttler | England | 24 | 665 | 55 | 28 | 39.11 | 143.31 |
| 8 | Virat Kohli | India | 25 | 1065 | 97 | 27 | 88.75 | 132.46 |
| 9 | DJ Bravo | West Indies | 34 | 530 | 35 | 25 | 21.2 | 126.79 |
| 10 | DPMD Jayawardene (SL) | Sri Lanka | 31 | 1016 | 111 | 25 | 39.07 | 134.74 |
