#4 Barry Sanders, 1989
The Detroit Lions picked Barry Sanders with their third overall pick in the 1989 Draft, after a remarkable college career with the Oklahoma State Cowboys team.
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Barry had an immediate impact in his rookie season, winning the NFL Rookie of the Year honours.
Through his ten seasons at Detroit, he averaged an astounding 1,500 rushing yards per season and close to 100 rushing yards per game! He was crowned the NFL's Most Valuable Player in 1997 and won the NFL Offensive Player of the Year title twice (1994, '97).