Week 1 is finally here. The Arizona Cardinals are looking to pick up their first win on the road against the very formidable Tennessee Titans. The Cardinals will want to start strong in their division, where the retooled 49ers also look to make some noise. The Titans shocked everyone by getting to the AFC Championship game in 2019, which they will likely want to replicate this season.Fixture - Arizona Cardinals vs Tennesee Titans | 2021 Regular seasonDate & Time - Sunday, September 12th, 1:00 PM EST.Venue - Nissan Stadium, Nashville, TennesseeArizona Cardinals previewThe Arizona Cardinals face a tough road matchup against the Tennessee Titans. The Cardinals will look to break their mediocre 2020 season after going 8-8 on the season. The Cardinals will lean heavily on Kyler Murray to use his pocket escaping ability against this Titans defense.Key Player - J.J. WattNormally this is where Kyler Murray's name should be, but the offseason has been kind to the Cardinals. J.J. Watt, even in his older football age, is still one of the most explosive edge rushers in the game. The Cardinals will want to utilize all of Watt's skills with Chandler Jones to help rattle Ryan Tannehill enough to make him commit many mistakes.Your 2021 Team Captains:@K1 @buddabaker32 @DeAndreHopkins @DGardeck @chanjones55 @JordanHicks Rodney Hudson@74_hump @JJWatt #RedSea pic.twitter.com/6bUcf9mbKZ— Arizona Cardinals (@AZCardinals) September 8, 2021Arizona Cardinals projected lineupQuarterback - Kyler Murray, Colt McCoy, Chris StrevelerRunning back - Chase Edmonds, James Conner, Jonathan Ward, Eno BenjaminWR - DeAndre Hopkins, Rondale Moore, A.J. Green, Andy Isabella, Christian KirkTE - Maxx Williams, Darrell Daniels, Demetrius HarrisOffensive Linemen - D.J. Humphries, Joshua Miles, Justin Pugh, Rodney Hudson, Max Garcia, Josh Jones, Justin Murray, Brian Winters, Kelvin Beachum, Josh JonesDefensive Line - J.J. Watt, Zach Allen, Michael Dogbe, Rashard Lawrence, Corey Peters, Leki FotuLinebacker - Chandler Jones, Victor Dimukeje, Zaven Collins, Jordan Hicks, Isaiah Simmons, Tanner Vallejo, Ezekiel Turner, Markus Golden, Devon KennardCornerback - Byron Murphy Jr., Marco Wilson, Luq Barcoo, Robert Alford, Tay GowanSafety - Jalen Thompson, Deionte Thompson, Budda Baker, Charles WashingtonKicker - Matt PraterPunter - Andy LeeReturners - Christian Kirk, Rondale Moore, Eno BenjaminTennesee Titans PreviewChicago Bears v Tennessee TitansThe Tennessee Titans have been one of the most successful teams behind leaders of their offense, Ryan Tannehill and Derrick Henry. The Titans are looking to make it to the postseason for their third straight year under Coach Vrabel. There could be more of a chance for the Titans to make it to the Super Bowl, with 17 games this season.Key Player - Derrick HenryDerrick Henry will finally have a better shot at breaking the all-time single-season rushing record. Henry came close in 2020 with 2,027 yards. Eric Dickerson still holds the current record with 2,105 yards. The Titans will look to Henry to continue his dominant rushing, but that could prove to be difficult with the defensive front of the Cardinals, who just added J.J. Watt.Tennesee Titans Projected LineupQuarterback - Ryan Tannehill, Logan WoodsideRunning back - Derrick Henry, Jeremy McNichols, Mekhi Sargent, Khari Blasingame (FB)WR - A.J. Brown, Julio Jones, Nick Westbrook-Ikhine, Chester Rogers, Cameron BatsonTE - Geoff Swaim, Anthony FirkserOffensive Linemen - Taylor Lewan, Rodger Saffold III, Aaron Brewer, Ben Jones, Aaron Brewer, Nate Davis, Dillon Radunz, David Quessenberry, Ty Sambrailo, Kendall LammDefensive Line - Jeffery Simmons, Teair Tart, Anthony Rush, Denico Autry, Larrell MurchisonLinebacker - Harold Landry III, Derick Roberson, Jayon Brown, Rashaan Evans, Monty Rice, Nick Dzubnar, Bud Dupree, Ola Adeniyi, Rashad WeaverCornerback - Janoris Jenkins, Kristian Fulton, Breon Borders, Caleb Farley, Elijah MoldenSafety - Amani Hooker, Matthias Farley, Kevin Byard, Dane CruikshankKicker - Sam FickenPunter - Brett KernReturners - Chester Rogers, Cameron BatsonCardinals vs Titans Match PredictionEven though the Cardinals have put more thought into their defensive front, there will be no stopping the dual passing and rushing attack that the Titans possess. The Titans will take this one, especially with playing on their home turf. 24-14 Titans.