Cardinals vs. Panthers projected starting lineup and depth chart for Week 2 | 2025 NFL season

The Carolina Panthers are hoping to bounce back in Week 2 against the Arizona Cardinals at State Farm Stadium after suffering a crushing defeat to the Jacksonville Jaguars in Week 1 to start the season.

The Cardinals, on the other hand, picked up a win in their first game of the season against the New Orleans Saints. They must be aware that they must beat the Cardinals, who have one of the NFL's weakest defenses, at home in their upcoming game if they hope to contend for an NFC West crown.

Check out the projected starting lineups for both the Cardinals and the Panthers ahead of their Week 2 game here.

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Arizona Cardinals vs. Carolina Panthers projected starting lineup for Week 2

Arizona Cardinals projected starting lineup

Kyler Murray of the Arizona Cardinals - Source: Getty

Here, we will take a look at how the Arizona Cardinals are projected to line up on offense to start the game against the Carolina Panthers on Sunday:

Position	Starter
QB	Kyler Murray
RB	James Conner
WR	Marvin Harrison Jr.
WR	Michael Wilson
WR	Zay Jones
TE	Trey McBride
LT	Paris Johnson Jr.
LG	Evan Brown
C	Hjalte Froholdt
RG	Isaiah Adams
RT	Jonah Williams

Below is how the Cardinals will likely line up in defense against the Panthers in Week 2:

Position	Starter
LDE	Josh Sweat
LDT	Calais Campbell
RDT	Dalvin Tomlinson
RDE	Darius Robinson
WLB	Akeem Davis-Gaither
MLB	Mack Wilson Sr.
SLB	Zaven Collins
LCB	Will Johnson
SS	Jalen Thompson
FS	Budda Baker
RCB	Max Melton
NB	Garrett Williams

Below is how the Cardinals' special teams are projected to line up to start the game against the Panthers:

Position	Starter
PK	Chad Ryland
P	Blake Gillikin
H	Blake Gillikin
PR	Greg Dortch
KR	Greg Dortch
LS	Aaron Brewer

Carolina Panthers projected starting lineup

Carolina Panthers starting quarterback Bryce Young - Source: Getty

Below is how the Carolina Panthers are expected to line up on offense to start the game against the Arizona Cardinals in Week 2:

Position	Starter
QB	Bryce Young
RB	Chuba Hubbard
WR	Tetairoa McMillan
WR	Xavier Legette
WR	Hunter Renfrow
TE	Ja'Tavion Sanders
LT	Ikem Ekwonu
LG	Damien Lewis
C	Austin Corbett
RG	Robert Hunt
RT	Taylor Moton

Below is how the Panthers are projected to line up in defense to start the game against the Cardinals:

Position	Starter
LDE	A'Shawn Robinson
NT	Bobby Brown III
RDE	Derrick Brown
WLB	Patrick Jones II
LLB	Christian Rozeboom
RLB	Trevin Wallace
SLB	D.J. Wonnum
LCB	Mike Jackson
SS	Tre'von Moehrig
FS	Nick Scott
RCB	Jaycee Horn
NB	Chau Smith-Wade

Below is how the Panthers' special teams are projected to line up to start the game against the Cardinals:

Position	Starter
PK	Ryan Fitzgerald
P	Sam Martin
H	Sam Martin
PR	Trevor Etienne
KR	Trevor Etienne
LS	JJ Jansen

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Arizona Cardinals vs. Carolina Panthers depth chart

Arizona Cardinals depth chart

Below is a look at the Arizona Cardinals’ offensive depth chart:

Position	Starter	2nd	3rd	4th
QB	Kyler Murray	Jacoby Brissett	-	-
RB	James Conner	Trey Benson	Emari Demercado	Bam Knight
WR	Marvin Harrison Jr.	Greg Dortch	Trishton Jackson (IR)	-
WR	Michael Wilson	Xavier Weaver	-	-
WR	Zay Jones	Simi Fehoko	-	-
TE	Trey McBride	Tip Reiman (out)	Elijah Higgins	Travis Vokolek
LT	Paris Johnson Jr.	Kelvin Beachum	Valentin Senn (IR)	-
LG	Evan Brown	Hayden Conner (IR)	-	-
C	Hjalte Froholdt	Jon Gaines II	-	-
RG	Isaiah Adams	Will Hernandez	-	-
RT	Jonah Williams	Josh Fryar	Christian Jone (IR)	-

Below is a look at the Cardinals’ defensive depth chart:

Position	Starter	2nd	3rd	4th
LDE	Josh Sweat	Jordan Burch	Xavier Thomas	-
LDT	Calais Campbell	L.J. Collier	Walter Nolen III (out)	Justin Jones (IR)
RDT	Dalvin Tomlinson	PJ Mustapha	-	-
RDE	Darius Robinson	Dante Stills	Bilal Nichols	-
WLB	Akeem Davis-Gaither	Owen Pappoe	-	-
MLB	Mack Wilson Sr.	Cody Simon (out)	J.J. Russell (IR)	-
SLB	Zaven Collins	Baron Browning	BJ Ojulari	-
LCB	Will Johnson	Elijah Jones	Sean Murphy-Bunting	-
SS	Jalen Thompson	Dadrion Taylor-Demerson	-	-
FS	Budda Baker	Kitan Crawford	Joey Blount (IR)	-
RCB	Max Melton	Denzel Burke	Starling Thomas V (IR)	-
NB	Garrett Williams	Kei'Trel Clark	-	-

Below is a look at the Cardinals’ special teams depth chart:

Position	Starter	2nd	3rd
PK	Chris Ryland	-	-
P	Blake Gillikin	-	-
H	Blake Gillikin	-	-
PR	Greg Dortch	Xavier Weaver	-
KR	Greg Dortch	Xavier Weaver	-
LS	Aaron Brewer	-	-

Carolina Panthers depth chart

Here is a look at the Carolina Panthers' offensive depth chart:

Position	Starter	2nd	3rd	4th
QB	Bryce Young	Andy Dalton	-	-
RB	Chuba Hubbard	Rico Dowdle	Trevor Etienne	Jonathon Brooks (out)
WR	Tetairoa McMillan	Brycen Tremayne	Dalevon Campbell	-
WR	Xavier Legette	David Moore	Jalen Coker (IR)	-
WR	Hunter Renfrow	Jimmy Horn Jr.	-	-
TE	Ja'Tavion Sanders	Tommy Tremble	Mitchell Evans	James Mitchell
LT	Ikem Ekwonu	Yosh Nijman	Brady Christiansen	-
LG	Damien Lewis	Chandler Zavala	-	-
C	Austin Corbett	Cade Mays	-	-
RG	Robert Hunt	-	-	-
RT	Taylor Moton	Yosh Nijman	-	-

Below is a look at the Panthers’ defensive depth chart:

Position	Starter	2nd	3rd
LDE	A'Shawn Robinson	Tershawn Wharton (out)	Popo Aumavae (IR)
NT	Bobby Brown III	Cam Jackson	-
RDE	Derrick Brown	Jaden Crumedy	LaBryan Ray (IR)
WLB	Patrick Jones II	Princely Umanmielen	Thomas Incoom
LLB	Christian Rozeboom	-	-
RLB	Trevin Wallace	Claudin Cherelus	Bam Martin-Scott
SLB	D.J. Wonnum	Nic Scourton	DJ Johnson
LCB	Mike Jackson	Akayleb Evans	Demarri Mathis (IR)
SS	Tre'von Moehrig	Demani Richardson	-
FS	Nick Scott	Lathan Ransom	-
RCB	Jaycee Horn	Corey Thornton	-
NB	Chau Smith-Wade	-	-

Below is a look at the Panthers’ special teams depth chart:

Position	Starter	2nd	3rd	4th
PK	Ryan Fitzgerald	-	-	-
P	Sam Martin	-	-	-
H	Sam Martin	-	-	-
PR	Trevor Etienne	David Moore	Jimmy Horn Jr.	-
KR	Trevor Etienne	Rico Dowdle	Davis Moore	Jimmy Horn Jr.
LS	JJ Jansen	-	-	-

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How to watch the Cardinals vs. Panthers Week 2 game? TV schedule and live stream details

Sunday's game against the Carolina Panthers at State Farm Stadium will give the Arizona Cardinals a chance to win the opening two games of a regular season for the first time since 2021.

The Week 2 game between the Cardinals and Panthers will start at 4:05 p.m. ET on CBS, with commentary from Spero Dedes (play-by-play), Adam Archuleta (color analyst), and Aditi Kinkhabwala (sideline reporter).

Fans may also stream the game on Paramount+ and FuboTV.

Game info:

Date and Time: Sunday, Sept. 14 at 4:05 p.m. ET

Location: State Farm Stadium, Glendale, Arizona

TV: CBS

Announcers: Spero Dedes (play-by-play), Adam Archuleta(color analyst), Aditi Kinkhabwala (sideline reporter)

Live Streaming: Paramount+, FuboTV