The Indianapolis Colts will host the New York Jets in the Week 9 opener of the 2021 NFL season on Thursday Night Football.The Colts are coming off a deflating loss at the hands of the Titans, while the Jets pulled off one of the biggest upset wins of the 2021 NFL season, beating the Cincinnati Bengals in Week 8.NFL@NFLFINAL: The @nyjets win in Mike White's first start! #TakeFlight #CINvsNYJ1:55 AM · Nov 1, 20215997618FINAL: The @nyjets win in Mike White's first start! #TakeFlight #CINvsNYJ https://t.co/hVXlp2caqLThe Colts' loss heavily dented their playoff odds and nothing less than a win on Thursday night would suffice if they are to keep their hopes of snagging a wild-card spot alive. The Jets aren't under much pressure but could do with another big win in head coach Robert Saleh's rookie season as head coach.Colts vs. Jets match detailsWhen: Thursday, November 4th, 8:20 pm ETWhere: Lucas Oil Stadium, Indianapolis, IndianaColts vs. Jets betting oddsSpreadsColts: -10.5 (-115)Jets: +10.5 (-115)MoneylineColts: -535Jets: +385TotalsColts: U46.0 (-110)Jets: O46.0 (-110)Colts vs. Jets picksWith T.Y. Hilton out, the Colts will again rely on young wide receiver Michael Pittman Jr. to be their X-factor in the passing game. Carson Wentz should have a good outing against a Jets team that's allowing 275 passing yards per game to opposing quarterbacks. Expect Wentz to throw for over 300 yards and Pittman to catch for at least 100.Dov Kleiman@NFL_DovKleimanMichael Pittman is turning to a legit #1 WR1:42 AM · Nov 1, 2021688Michael Pittman is turning to a legit #1 WRhttps://t.co/sRjrP87sWoColts vs. Jets key injuriesIndianapolis ColtsWR T.Y. Hilton (Quad): OutCB BoPete Keyes (Hamstring): QuestionableS Khari Willis (Calf): OutG Quenten Nelson (Toe): QuestionableNew York JetsRB Tevin Coleman (Hamstring): OutWR Corey Davis (Hip): DoubtfulQB Zach Wilson (Knee): OutColts vs. Jets head-to-headThe Colts and Jets have faced every 75 times in the NFL. Indianapolis holds a 43-32 lead in all-time head-to-head games between the two teams.However, the Jets have won four of their last six games against the Colts.Colts vs. Jets PredictionThe spirits are high in New York, but their defense is still one of the worst in the NFL and that won't change in the space of three days since their last win. The Colts suffered a bad loss in Week 8 but are a much better team than the Jets.Prediction: The Colts' defense come through in the clutch to help their team secure a close win.