Fantasy Football Start 'Em Sit 'Em NFL Week 4 2022: Running back rankings

NFL Fantasy Football Running Backs - Sit 'Em

#1 - Cam Akers

NFL - Los Angeles Rams v Arizona Cardinals

While Cam Akers of the Los Angeles Rams had his best outing of the year in Week 3 against the Arizona Cardinals, you should sit him if possible here.

The Rams will come up against one of the best run-defenses in football in the San Francisco 49ers who've allowed just 16.3 FPPG so far in 2022. Akers has also continued to split carries with Darrell Henderson. This makes the pair of Rams backs a risky start in fantasy football.

#2 - Clyde Edwards-Helaire

Kansas City Chiefs v Indianapolis Colts

Kansas City Chiefs running back Clyde Edwards-Helaire will have his work cut out when they face a tough Tampa Bay Buccaneers defense in Week 4.

The Buccaneers have allowed the fewest FPPG to running backs in 2022, at just 9.5. This is despite facing the dangerous duo of Aaron Jones and A.J. Dillon in Week 3.

Edwards-Helaire has been as good through the air as on the ground in 2022, with two touchdowns thus far. However, he was awful on the ground in the Chiefs' defeat to the Indianapolis Colts, taking seven carries for zero total yards. Sit him this week in a tough matchup.

#3 - Jeff Wilson Jr.

San Francisco 49ers v Denver Broncos

Jeff Wilson Jr. of the San Francisco 49ers is also a sit candidate for Week 4. Wilson was decent enough against the Broncos in Week 3. He rushed 12 times for 75 yards and topping 100 yards from total scrimmage.

San Francisco goes into Week 4 facing a tough L.A. Rams defense that has allowed just 9.9 FPPG to running backs so far in 2022. This is the second-lowest total in the NFL. The Niners also look to be without stud left tackle Trent Williams, who is dealing with a high-ankle sprain.