While it may be an ordinary game for some, the showdown between the 6-4 Arizona Cardinals and 4-6 New England Patriots will be something to watch, as both teams fight to keep their playoff hopes alive.The Cardinals are coming off a tough defeat against their NFC West rival Seattle Seahawks on "Thursday Night Football," losing 28-21. As for the Patriots, they are also coming off a loss against the Houston Texans, falling 27-20 last week and slipping farther behind the AFC East leaders, the Buffalo Bills.Arizona Cardinals at New England Patriots Betting OddsCardinals odds: -114Patriots odds: -106Arizona is a -2.5 favorite over New England on SundayArizona Cardinals at New England Patriots Picks1. New England Patriots quarterback Cam Newton will have two rushing touchdowns.2. Arizona Cardinals quarterback Kyle Murray will have at least 300 passing yards.3. Bill Belichick will run a trick play against the Cardinals' defenseArizona Cardinals at New England Patriots Key NotesPatriots QB Cam Newton has thrown only four touchdown passes this seasonHowever, Newton has not thrown a single interception since Week 7 against the 49ersPatriots RB Damien Harris is already having a career-high season, with 514 rushing yards to dateCardinals QB Kyler Murray was on the injury report this week, however he was removedDespite their 4-6 record, the Patriots are still in a hunt for a playoff spot and are fighting with the Dolphins for one in the AFC EastArizona's defense is allowing 367.7 yards per game (19th in the league)The rivalry between Cardinals WR DeAndre Hopkins and Patriots CB Stephon Gilmore will continue on, making it a good game and matchup between two of the league's best at their positions.The all-time series between these two teams is tied at 7-7The last time these two teams met was in 2016, when the Patriots defeated Arizona 26-21Both teams stand at 3rd place in their respective divisionsWhat a catch by @LookIn_Da_Miere! 📺: @NFLonCBS pic.twitter.com/qIn7o7jp6k— New England Patriots (@Patriots) November 22, 2020Arizona Cardinals at New England Patriots Key InjuriesArizona Cardinals:WR Larry Fitzgerald (illness) is outDE Josh Mauro (hamstring) is outS Jalen Thompson (ankle) is outNew England Patriots:CB Stephon Gilmore (knee) is questionableRB Damien Harris (ankle, chest) is questionableOL Shaq Mason (calf) is questionableArizona Cardinals at New England Patriots PredictionPrediction: Patriots 20, Cardinals 17Money Line: Arizona -144, Patriots +122Against The Spread: Arizona 6-4, Patriots 4-6