One undefeated and two winless teams remain as we enter Week 5 of the 2021 NFL season.The Cincinnati Bengals lead the AFC North and the LA Chargers lead the AFC West through four weeks. Meanwhile, the Kansas City Chiefs and Pittsburgh Steelers remain fourth in their division.There have been six games that went into overtime, with at least one in each of the four weeks. The single-season record of 25 overtime games was set back in 2002.Week 5 begins with Thursday Night Football between the LA Rams and Seattle Seahawks. And here's a betting guide for those who want an edge this week.NFL Thursday Night Football - LA Rams at Seattle SeahawksSeattle Times Sports@SeaTimesSports🟢 The Seahawks are breaking out the ‘Action Green’ for their Thursday night showdown with the Rams.Seattle is 4-0 while wearing the jerseys, per @seahawksPR.4:18 AM · Oct 5, 202136431🟢 The Seahawks are breaking out the ‘Action Green’ for their Thursday night showdown with the Rams.Seattle is 4-0 while wearing the jerseys, per @seahawksPR. https://t.co/SEz06AjuMfSpread - LA Rams -2.5 pointsMoney Line - LA Rams -134, Seattle Seahawks +114Over/Under - 54.5Additional Prop Bet Pick - QB Matthew Stafford to have over 305 passing yards (-114)Game Picks - LA Rams to win (-134) and cover the spread (-105), over 54.5 points (-115)Game Prediction - LA Rams 36 - Seattle Seahawks 29New York Jets at Atlana Falcons - LondonDerek Topper@DerekTopperThankfully, the Jets and Falcons will have no trouble FLYING there. twitter.com/nfluk/status/1…NFL UK@NFLUKFOOTBALL IS COMING TO LONDON!@NYJets vs @AtlantaFalcons🇬🇧🏟️ @SpursOfficial10:03 AM · Oct 5, 20213414FOOTBALL IS COMING TO LONDON!@NYJets vs @AtlantaFalcons🇬🇧🏟️ @SpursOfficial https://t.co/ousW5BV1211:49 AM · Oct 11, 2018Thankfully, the Jets and Falcons will have no trouble FLYING there. twitter.com/nfluk/status/1…Spread - Atlanta Falcons -3 pointsMoney Line - New York Jets +138, Atlanta Falcons -164Over/Under - 46.5Additional Prop Bet Pick - 1st Drive results in Field Goal Attempt +410Game Picks - Atlanta Falcons to win (-164) and cover the spread (-115), under 46.5 points (-115)Game Prediction - Atlanta Falcons 23 - New York Jets 17Philadelphia Eagles at Carolina Panthers𓃵@Goaty_SznThe Carolina Panthers next 5 opponents have a combined record of 5-14Eagles (1-3)Vikings (1-3)Giants (1-3)Falcons (1-3)Patriots (1-2) Currently playing BucsA very good bounce back Schedule10:49 AM · Oct 3, 202147753The Carolina Panthers next 5 opponents have a combined record of 5-14Eagles (1-3)Vikings (1-3)Giants (1-3)Falcons (1-3)Patriots (1-2) Currently playing BucsA very good bounce back ScheduleSpread - Carolina Panthers -3.5 pointsMoney Line - Philadelphia Eagles +158, Carolina Panthers -188Over/Under - 44.5Additional Prop Bet Pick - Carolina Panthers total home team points over 24 (-116)Game Picks - Carolina Panthers to win (-188) and cover the spread (-114), over 44.5 points (-114)Game Prediction - Carolina Panthers 26 - Philadelphia Eagles - 20Miami Dolphins at Tampa Bay BuccaneersOddsChecker@OddsCheckerUS☀️The Battle of Florida☀️@Buccaneers and @MiamiDolphins go head-to-head to see who reigns supreme in the sunshine state.🏈#NFL expert @MattOLearyNY takes you through his picks and predictions for Sunday's matchup. ⬇️buff.ly/3aaJ04G10:25 AM · Oct 5, 202151☀️The Battle of Florida☀️@Buccaneers and @MiamiDolphins go head-to-head to see who reigns supreme in the sunshine state.🏈#NFL expert @MattOLearyNY takes you through his picks and predictions for Sunday's matchup. ⬇️buff.ly/3aaJ04GSpread - Tampa Bay Buccaners -10.5 pointsMoney Line - Miami Dolphins +380, Tampa Bay Buccaneers -490Over/Under - 47.5Additional Prop Bet Pick - Total number of TDs scored by away team Miami Dolphins over 2 (+100)Game Picks - Tampa Bay Buccaneers win (-490), do not cover the spread (-114), under 47.5 pointsGame Prediction - Tampa Bay Buccaneers 23 - Miami Dolphins - 17New Orleans Saints at WashingtonJeff Nowak@Jeff_NowakMichael Thomas won't be eligible to play in Week 5, but he was one of the last people out of the #Saints' facility on Monday.Why? In part b/c he spent an hour talking with WRs coach Curtis Johnson as he went over the gameplan for Washington.More ⤵️audacy.com/wwl/local-spor…1:41 AM · Oct 5, 202120634Michael Thomas won't be eligible to play in Week 5, but he was one of the last people out of the #Saints' facility on Monday.Why? In part b/c he spent an hour talking with WRs coach Curtis Johnson as he went over the gameplan for Washington.More ⤵️audacy.com/wwl/local-spor…Spread - New Orleans Saints -2.5 pointsMoney Line - New Orleans Saints -132, Washington +112Over/Under - 44.5Additional Prop Bet Pick - Highest scoring quarter - 1st quarter (+550)Game Picks - Washington wins (+112), over 44.5 points (-110)Game Prediction - Washington 27 - New Orleans Saints 21Tennessee Titans at Jacksonville JaguarsPreston Penn@TheRealPres10Days since the @jaguars last won a game: 382Days since the Jags last beat the Titans: 74212:05 PM · Oct 1, 202111015Days since the @jaguars last won a game: 382Days since the Jags last beat the Titans: 742Spread - Tennessee Titans -4 pointsMoney Line - Tennessee Titans -200, Jacksonville Jagaurs +168Over/Under - 48.5Additional Prop Bet Pick - Jacksonville Jaguars to win and total score under 48.5 (+240)Game Picks - Jacksonville Jaguars win (+168), under 48.5 points (-114)Game Prediction - Jacksonville Jaguars 23 - Tennesee Titans 21Detroit Lions at Minnesota VikingsDustin Baker@DustBakerThe Vikings are the only team in the NFC North thru 4 weeks to cumulatively outscore opponents. Vikings (+2)Packers (-5)Bears (-27)Lions (-38)And yet, they're 1-3.1:12 AM · Oct 4, 202155951The Vikings are the only team in the NFC North thru 4 weeks to cumulatively outscore opponents. Vikings (+2)Packers (-5)Bears (-27)Lions (-38)And yet, they're 1-3.Spread - Minnesota Vikings -7.5 pointsMoney Line - Detroit Lions +280, Minnesota Vikings -350Over/Under - 49.5Additional Prop Bet Pick - Total TDs scored in game over 5.5 (-116)Game Picks - Minnesota Vikings win (-350), do not cover the spread (-115), over 49.5 points (-106)Game Prediction - Minnesota Vikings 29 - Detroit Lions 27Denver Broncos at Pittsburgh SteelersPittsburgh Steelers@steelersBack home to take on the Broncos.#HereWeGo | #CrucialCatch | @UPMC | @UPMCHillmanCC8:13 AM · Oct 5, 20211536139Back home to take on the Broncos.#HereWeGo | #CrucialCatch | @UPMC | @UPMCHillmanCC https://t.co/OfvWgOauS4Spread - Pittsburgh Steelers -1.5 pointsMoney Line - Denver Broncos -104, Pittsburgh Steelers -112Over/Under - 39.5Additional Prop Bet Pick - Total FGs in 1st half over 1.5 (-102)Game Picks - Pittsburgh Steelers win (-112) and cover the spread (-105), under 39.5 points (-105)Game Prediction - Pittsburgh Steelers 19 - Denver Broncos 17Green Bay Packers at Cincinnati BengalsGreen Bay Packers@packers.@ajdillon7's impact, defense on the rise + a look ahead to the Bengals. Packers Daily ⤵️5:29 AM · Oct 5, 202151135.@ajdillon7's impact, defense on the rise + a look ahead to the Bengals. Packers Daily ⤵️ https://t.co/7igTQzXW1GSpread - Green Bay Packers -3 pointsMoney Line - Green Bay Packers -164, Cincinnati Bengals +138Over/Under - 50.5Additional Prop Bet Pick - Both teams to score 2+ TDs in each half (+1650)Game Picks - Green Bay Packers to win (-164) and cover the spread (-110), over 50.5 points (-110)Game Prediction - Green Bay Packers 35 - Cincinnati Bengals 31New England Patriots at Houston TexansWCVB-TV Boston@WCVBJUST IN: The Patriots have placed their left tackle and left guard on the COVID-19 list as the team prepares for next week's game against the #Texans.5:04 AM · Oct 5, 2021149JUST IN: The Patriots have placed their left tackle and left guard on the COVID-19 list as the team prepares for next week's game against the #Texans. https://t.co/yroBrRGQBiSpread - New England Patriots -8.5 pointsMoney Line - New England Patriots -400, Houston Texans +315Over/Under - 39.5Additional Prop Bet Pick - Both teams score at least 15 points (+132)Game Picks - New England Patriots win (-400) and cover the spread (-110), over 39.5 points (-110)Game Prediction - New England Patriots 27 - Houston Texans 15Chicago Bears at Las Vegas RaidersMaximBet@MaximBetUSAMontgomery is out. The Bears are +4.5 at the Raiders this week. twitter.com/DanGrazianoESP…Dan Graziano@DanGrazianoESPNPer source, tests showed Bears RB David Montgomery has a knee sprain that’s expected to keep him out 4-5 weeks. Not season-ending, but Bears will be without their starting RB for a while.10:10 AM · Oct 5, 2021510Per source, tests showed Bears RB David Montgomery has a knee sprain that’s expected to keep him out 4-5 weeks. Not season-ending, but Bears will be without their starting RB for a while.1:49 AM · Oct 11, 2018Montgomery is out. The Bears are +4.5 at the Raiders this week. twitter.com/DanGrazianoESP…Spread - Las Vegas Raiders -5.5 pointsMoney Line - Chicago Bears +198, Las Vegas Raiders -240Over/Under - 45Additional Prop Bet Pick - Highest scoring quarter - 4th quarter (+220)Game Picks - Las Vegas Raiders win (-240) and cover the spread (-110), under 45 points (-110)Game Prediction - Las Vegas Raiders 23 - Chicago Bears 14Cleveland Browns at LA ChargersDov Kleiman@NFL_DovKleimanMost QB pressures so far this season 1) #Titans Harold Landry2) #Chargers Joey Bosa3) #Browns Myles Garrett9:30 AM · Oct 5, 20211686232Most QB pressures so far this season 1) #Titans Harold Landry2) #Chargers Joey Bosa3) #Browns Myles Garrett https://t.co/iQw674It44Spread - LA Chargers -1.5 pointsMoney Line - Cleveland Browns +100, LA Chargers -118Over/Under - 46.5Additional Prop Bet Pick - Cleveland Browns to win and under 41.5 points scored in game (+430)Game Picks - Cleveland Browns win (+100), under 46.5 points (-105)Game Prediction - Cleveland Browns 20 - LA Chargers 19New York Giants at Dallas CowboysPatrik [No C] Walker@VoiceOfTheStarJaylon Smith has been released by the #Cowboys ahead of their Week 5 matchup with the Giants, and while moving on from him in 2021 wasn't unexpected -- the timing and call to release him outright raises questions.And here are the answers:DETAILS ⬇️ cbssports.com/nfl/news/cowbo…9:24 AM · Oct 5, 202124366Jaylon Smith has been released by the #Cowboys ahead of their Week 5 matchup with the Giants, and while moving on from him in 2021 wasn't unexpected -- the timing and call to release him outright raises questions.And here are the answers:DETAILS ⬇️ cbssports.com/nfl/news/cowbo…Spread - Dallas Cowboys -7 pointsMoney Line - New York Giants +260, Dallas Cowboys -320Over/Under - 52.5Additional Prop Bet Pick - 1st Drive results in offensive TD (+260)Game Picks - Dallas Cowboys win (-320) and cover the spread (-110), under 52.5 points (-115)Game Prediction - Dallas Cowboys 29 - New York Giants - 20San Francisco 49ers at Arizona Cardinals49ers on NBCS@NBCS49ersKyle Shanahan is confident Trey Lance will be prepared should the 49ers QB have to make his first NFL start vs. the Cardinalsbit.ly/3uQ3lpp1:58 AM · Oct 5, 202178242Kyle Shanahan is confident Trey Lance will be prepared should the 49ers QB have to make his first NFL start vs. the Cardinalsbit.ly/3uQ3lpp https://t.co/Mv9sIR7c6xSpread - Arizona Cardinals -5.5 pointsMoney Line - San Francisco 49ers +205, Arizona Cardinals -250Over/Under - 50.5Additional Prop Bet Pick - Arizona Cardinals total TDs under 3 (+114)Game Picks - Arizona Cardinals win (-250) and cover the spread (-110), under 50.5 points (-118)Game Prediction - Arizona Cardinals 23 - San Francisco 49ers 16Sunday Night Football - Buffalo Bills at Kansas City Chiefsnick wright@getnickwrightBills have outscored their opponents 118-21 over their last 3… and no one is going to care when they go to Arrowhead next week and get beat down by the Chiefs, once again. Sad!3:52 AM · Oct 3, 2021177397Bills have outscored their opponents 118-21 over their last 3… and no one is going to care when they go to Arrowhead next week and get beat down by the Chiefs, once again. Sad!Spread - Kansas City Chiefs -3 pointsMoney Line - Buffalo Bills +126, Kansas City Chiefs -148Over/Under - 56.5 pointsAdditional Prop Bet Pick - Total TDs scored under 6.5 (-102)Game Picks - Buffalo Bills win (+126), under 56.5 points (-110)Game Prediction - Buffalo Bills 24 - Kansas City Chiefs 21Monday Night Football - Indianapolis Colts at Baltimore RavensKevin Oestreicher@koestreicher34In honor of it being Colts week for the Ravens, here’s a video of Ray Lewis’ final snap at M&T Bank Stadium6:15 AM · Oct 5, 20212266394In honor of it being Colts week for the Ravens, here’s a video of Ray Lewis’ final snap at M&T Bank Stadium https://t.co/jbjwgJctBCSpread - Baltimore Ravens -7 pointsMoney Line - Indianapolis Colts +265, Baltimore Ravens -330Over/Under - 46.5Additional Prop Bet Pick - Baltimore Ravens win by 1-13 points (+145)Game Picks - Baltimore Ravens win (-330), do not cover spread (-110), under 46.5 points (-115)Game Prediction - Baltimore Ravens 23 - Indianapolis Colts 20Also Check Out: Complete NFL Week 5 TV Schedule