Pro Bowl quarterback Deshaun Watson and the Houston Texans travel to Nissan Stadium in Nashville on Sunday to take on Pro Bowl running back Derrick Henry and the Tennessee Titans.The Titans (4-0) have a quick turnaround after their Week 5 game with the Buffalo Bills was pushed to this past Tuesday due to a COVID-19 outbreak among Titans players and staff. Despite missing some players for that game who had tested positive, Tennessee scored a convincing 42-16 win over the previously unbeaten Bills. Only five days later, however, the Titans have to play the Texans.On the other side, the Texans (1-4) are coming off their first win of the season after firing head coach Bill O'Brien. They look to stay hot against the undefeated Titans.Tennessee Titans vs Houston Texans Head to HeadThe Tennessee Titans and Houston Texans have met each other 36 times in the past. The Titans currently have a slight edge in the series with a 19-17 record.The AFC South rivals last faced each other in 2019, when the Titans won in Houston, 35-14.Tennessee Titans form guide in the league: W W W WHouston Texans form guide in the league: L L L L WTennessee Titans vs Houston Texans Team NewsTwo names to watch on the Titans are receiver A.J. Brown and linebacker Jadeveon Clowney, both of whom did not practice on Wednesday. Both Brown and Clowney are nursing knee injuries, and the team likely held them out of practice for cautionary reasons. Tannehill should have his WR1 ready for Sunday and the Texans should still prepare for what is to come from the disruptive defender Clowney.Wednesday's Injury Report ahead of #HOUvsTEN.@Cigna | #WeAreTexans— Houston Texans (@HoustonTexans) October 14, 2020As for the Texans, there aren't either many significant injuries to watch. Star defensive lineman J.J. Watt did not practice due to a non-injury related issue. Tight end Jordan Atkins (ankle, concussion) also did not practice. The Texans are already severely hit with injuries on the defensive side, so having Watt play on Sunday would be a big boost for the team.Tennessee Titans vs Houston Texans Projected StartersTennessee Titans:QB: Ryan TannehillRB: Derrick HenryWR: A.J. Brown (Q), Adam Humphries, Kalif RaymondTE: Jonnu SmithBest On Target percentage:1. Russell Wilson - 83.9%2. Derek Carr - 83.5%3. Josh Allen - 83.2%4. Ryan Tannehill - 82.9%5. Teddy Bridgewater - 82.6%— ProFootballReference (@pfref) October 15, 2020Houston Texans:QB: Deshaun WatsonRB: David JohnsonWR: Will Fuller V, Brandin Cooks, Randall CobbTE: Jordan Akins (Q)Tennessee Titans vs Houston Texans PredictionThe Titans are certainly hot and considering this is the first division game between the two teams, it will certainly be a tough but fun game to watch. Tannehill is playing like an MVP quarterback currently and has wins against the Broncos, Jaguars, Vikings and Bills.It will be a tough game for the Texans, despite the fact that they no longer have their former head coach.Prediction: Titans win in relatively easy fashion.