The NFC North champion Green Bay Packers travel across the country to face the AFC North champion Buffalo Bills in the final week of the 2021 NFL preseason. The Bills are undefeated this preseason and will look to maintain that pristine record as they take on a Green Bay Packers squad hungry for their first win of this campaign.Here's a look at how you can watch Saturday afternoon's game and what the oddsmakers are predicting will happen.Green Bay Packers vs. Buffalo Bills | NFL Preseason Week 3How to watch, live streams, TV channel & moreStart time: 1 PM ET, August 28Location: Highmark Stadium, Orchard Park, Buffalo, New YorkTV Channel: NFL Network, Packers TV Network (Green Bay), NY: WIVB (Buffalo)Live stream option: NFL Game Pass"I'll continue to put in that work until I'm done playing football."@Showtyme_33 is never satisfied 😤 #GoPackGo pic.twitter.com/7wBDvRuJbS— Green Bay Packers (@packers) August 27, 2021Packers vs Bills | Current NFL odds, spreads, betting lines and predictionSpread: - 8.5 Buffalo BillsMoney line: Packers +280, Bills -370Total: 34.5 (Over -112, Under -108)The Bills are heavy favorites to win against a Packers squad without their starters this preseason. Buffalo, playing at home in front of its raucous fans, has oddsmakers confident in another victory this NFL preseason.Green Bay Packers vs Buffalo Bills series historyThe two teams have met each other 13 times, with the Buffalo Bills winning eight games and the Green Bay Packers winning five.Here are the last five meetings between the two teams in the NFL regular season.Packers 22-0 Bills | 2018Packers 13-21 Bills | 2014Packers 34-7 Bills | 2010Packers 10-24 Bills | 2006Packers 10-0 Bills | 2002The Green Bay Packers easily beat the Buffalo Bills in their last matchup back in 2018, but the teams have shared wins and losses in recent times.Just like they planned it! 😉 #BillsMafia @AndreSmith_9 | @TakeAwayTre_ pic.twitter.com/n6IOd57DFF— Buffalo Bills (@BuffaloBills) August 25, 2021Green Bay Packers 2021 preseason scheduleWeek 1 | vs. Houston Texans (L 26-7) | August 14Week 2 | vs. Philadelphia Eagles (L 23-14) | August 21Week 3 | At Buffalo Bills | August 28Buffalo Bills 2021 preseason scheduleWeek 1 | At Detroit Lions (W 16-15) | August 13Week 2 | At Chicago Bears (W 41 - 15) | August 21Week 3 | vs. Green Bay Packers | August 28