The San Francisco 49ers secured a 17-13 victory during their season opener against the Seattle Seahawks on Sunday. However, this win came at a heavy cost for Kyle Shanahan's team. Starting quarterback Brock Purdy and veteran tight end George Kittle both suffered injuries at Lumen Field, raising questions about their availability for Week 2.On Monday, NFL insider Adam Schefter provided an update on Purdy's injury. As per his tweet on X, the quarterback injured his left shoulder and toe during their showdown against the Seahawks. Thus, there is an air of uncertainty about his chances of making an appearance in Week 2."Brock Purdy has a left shoulder and toe injury that make him uncertain for Sunday's game in New Orleans. Kyle Shanahan said the team will see how the practice week goes. If Purdy cannot play, 49ers backup Mac Jones would be in line to start," Schefter tweeted.Fans took to social media to share their reactions to Purdy and George Kittle's injury concerns.Warren Sharp @SharpFootballLINKPurdy hurt... Kittle out... CMC's calf muscle is paper mache this is not up for debate, it's a fact, they are cursed 49ers health by season: 2024: #1 most injured 2023: #29 most injured ◄ 12-5, lost SB 2022: #9 most injured ◄ 13-4, lost NFCCG 2021: #3 most injured 2020: #1Dave Loughran @Loughy_DLINK@AdamSchefter I don’t believe in curses, but if I did it would be because of the 49ersJon from Maspeth @JonFromMaspethLINK@AdamSchefter Someone has a 49ers voodoo doll somewhere.OC21 @IAmOC21LINK@AdamSchefter Well that is less then idealDigital World @crypticworld7LINK@AdamSchefter Double whammy for NinersAgainst the Seahawks, Brock Purdy completed 26 of the 35 passes he attempted for 277 yards and two passing touchdowns. The 49ers were trailing 13-10 in the fourth quarter. However, with just over a minute left in the game, the quarterback found tight end Jake Tonges with a four-yard passing touchdown to seal the win for his team.Last season, the 49ers dealt with injury concerns to several of their key players. This resulted in them finishing fourth in the NFC West with a 6-11 record, failing to qualify for the playoffs a year after appearing in the Super Bowl. Purdy recorded 3,864 yards and 20 TDs passing for his team.In May, he signed a five-year extension worth $265 million. If the quarterback is unavailable for Week 2, then the team will have to put its faith in Mac Jones to lead the offense.How long will 49ers TE George Kittle be out?George Kittle suffered a hamstring injury in the first half of their season opener against the Seahawks. He did not make a return to the field later on, raising concerns about the severity of his situation.According to the update provided by Kyle Shanahan, Kittle will be unavailable for a few weeks as he recovers from his injury.Apart from him, Shanahan's team has Luke Farrell, Jake Tonges, and Brayden Willis on the TE depth chart.The 49ers take on the New Orleans Saints on Sept. 14 at Caesars Superdome. The game will be broadcast on FOX at 1:00 pm ET.