Fred Warner landed awkwardly and suffered a brutal injury in the first quarter on Sunday against the Tampa Bay Buccaneers. The San Francisco 49ers linebacker collided with Rachaad White and his teammate while blocking a rush. He went down and was carted off the field.NFL insider Adam Schefter posted a heartbreaking update on X."Cart is coming out for the injured 49ers LB Fred Warner. His right leg already has been put in an air cast," Schefter tweeted.Fans shared their reactions to Warner's injury."May his soul rest in peace," one fan wrote.zac @shaisprintLINK@AdamSchefter May his soul rest in peace"Prayers up for Fred🙏🏾💔," another fan wrote."That’s heartbreaking. An air cast almost always signals something severe. Huge loss for the 49ers if he’s out long-term," a fan said.Warner assisted with one tackle before he was carried off the field. The Buccaneers lead the 49ers 7-3 at the end of the first half. San Francisco is already struggling with multiple injuries and this only adds to their worries.