San Francisco 49ers Schedule 2021: Dates, Times, Opponents, Tickets & Season Prediction

After a disappointing season in 2020, the San Francisco 49ers will look to reclaim the NFC West title in the 2021 NFL season.

The 49ers will commence their new campaign with a road trip to Detroit to take on former franchise quarterback Jared Goff and the Lions. In addition to their NFC West rivals, the 49ers will host the Green Bay Packers, Indianapolis Colts, Atlanta Falcons, Minnesota Vikings and Houston Texans in 2021.

Their road schedule includes trips to Philadelphia and Jacksonville. Their abysmal record last season has led to the San Francisco 49ers being allotted just two primetime games in 2021.

San Francisco 49ers 2021 Schedule

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Week 1

Sunday, September 12, at Detroit Lions, 1:00 p.m. (FOX)

Week 2

Sunday, September 19, at Philadelphia Eagles, 1:00 p.m. (FOX)

Week 3

Sunday, September 26, Green Bay Packers, 8:20 p.m. (NBC)

Week 4

Sunday, October 3, Seattle Seahawks, 4:05 p.m. (FOX)

Week 5

Sunday, October 10, at Arizona Cardinals, 4:25 p.m. (FOX)

Week 6

BYE

Week 7

Sunday, October 24, Indianapolis Colts, 8:20 p.m. (NBC)

Week 8

Sunday, October 31, at Chicago Bears, 1:00 p.m. (FOX)

Week 9

Sunday, November 7, Arizona Cardinals, 4:25 p.m. (FOX)

Week 10

Monday, November 15, Los Angeles Chargers, 8:15 p.m. (ESPN)

Week 11

Sunday, November 21, at Jacksonville Jaguars, 1:00 p.m. (FOX)

Week 12

Sunday, November 28, Minnesota Vikings, 4:25 p.m. (FOX)

Week 13

Sunday, December 5, at Seattle Seahawks, 8:20 p.m. (NBC)

Week 14

Sunday, December 12, at Cincinnati Bengals, 1:00 p.m. (CBS)

Week 15

Sunday, December 19, Atlanta Falcons, 4:05 p.m. (CBS)

Week 16

Sunday, December 23, at Tennessee Titans, 8:20 p.m. (NFL Network)

Week 17

Sunday, January 2, Houston Texans, 4:05 p.m. (CBS)

Week 18

Sunday, January 9, at Los Angeles Chargers, 4:25 p.m. (FOX)

How much do San Francisco 49ers tickets cost?

Tickets for the San Francisco 49ers' games start at around $175 each and can cost up to $2,000 or more.

How do you get the San Francisco 49ers tickets for the 2021 season?

The single-game tickets for the 49ers' games in 2021 will go on sale on Thursday, May 13, and can be purchased through the 49ers website which will redirect you to TicketMaster.

San Francisco 49ers Season Prediction: 9-8

The 49ers are yet to solve their quarterback conundrum, which could hurt the team in 2021 given how competitive the NFC West is.

About the author

Bethany Cohen is an NFL writer at Sportskeeda, with a rich prior 15-year experience in the sports writing industry, primarily covering the MLB and MiLB. She majored in Communications from the University of South Florida and has previously worked for top companies such as Examiner.com and Legends on Deck.

Bethany owes her NFL allegiance to the Pittsburgh Steelers owing to their long-standing tradition and competitiveness. She is a fan of old stalwarts such as Terry Bradshaw and Franco Harris and would love to watch them in the 1970s if she manages to get her hand on a time machine. She also acknowledges the greatness of modern icons like T.J. Watt for his desire to continuously improve despite being on top. She admires coaches Mike Tomlin and Andy Reid for their longevity and success.

The ace reporter credits her knowledge and love for the sport to be her biggest reporting strengths. Prior fact-checking is a big component of her process and she always scours through additional sources to ensure complete accuracy in her content.

Super Bowl XLIII, when the Steelers won the the grand prize after Santonio Holmes’ epic catch in the end zone with just seconds left on the clock is etched in Bethany’s memory forever. When she is free of her professional commitments, she likes to attend sports events and music concerts.

Know More

49ers Fans! Check out the latest San Francisco 49ers Schedule and dive into the 49ers Depth Chart for NFL Season 2024-25.

Edited by Jay Lokegaonkar