The San Francisco 49ers received a big blow from George Kittle after the veteran tight end exited the field with a hamstring injury. Despite starting their Week 1 matchup against the Seattle Seahawks 7-0, they received 10 unanswered points in the second quarter to enter halftime down 10-7.Kittle suffered the injury late in the first half to end a promising start to the game and the season. The 49ers announced that he was ruled out for the rest of the contest."Injury Update: George Kittle (hamstring) is out for the rest of the game."Before going down, Kittle had four catches for 25 yards, including the first touchdown of the game to give the Niners the first lead.Kittle came off a 15-game season in which he caught 78 passes for 1,106 yards and eight touchdowns, at times being the most dangerous threat of a team that missed RB Christian McCaffrey and WR Brandon Aiyuk.Aiyuk wasn't available for today's game, either, so losing Kittle was a big blow for Kyla Shanahan's team.Luke Farrell and Jake Tonges are the only two available tight ends the 49ers have for this game.George Kittle shared thoughts on potential Hall of Fame trajectory ahead of 2025 seasonBack in July, while he prepared for the new season, NFL analyst Kay Adams told George Kittle that he was en route to having a Hall of Fame tight end career. Kittle showed his surprise about that possibility, but explained his main goal was to stay healthy."Oh, my goodness. If I just continue to stay healthy and play at a high level, all I ever do is try to compete with myself as best I possibly can and always challenge myself. You know, my old tight ends coach always gave me a note card at the beginning of every season and he said, 'your goal is to have 1000 yards, 10 touchdowns and a ton of pancakes.'"I haven't gotten 10 touchdowns every season, that would be really fun, but trending in that direction now. So hopefully get a bunch of touchdowns, a bunch of yards, and just focus on that. Whatever comes after that, comes after that. But I'm just going to enjoy."There's no doubt he can finish his career as a future Hall of Famer, but this injury scare could derail his plans for 2025.