The New England Patriots were led to a 25-6 victory over the New York Jets by rookie quarterback Mac Jones, who showed that he is on his way to a solid rookie season. The Patriots also showed that their rookie quarterback is in a better situation than their divisional foes the New York Jets and Zach Wilson.For the New Orleans Saints, the team is in its first "post-Drew Brees season" and in Week 1, looked dominant in a win over the Green Bay Packers. In a Week 2 division game against the Carolina Panthers, the Saints struggled and were defeated 26-7.NFL on CBS 🏈@NFLonCBSPasser rating through Week 2:Mac Jones: 96.7Trevor Lawrence: 57.1Zach Wilson: 56.14:44 AM · Sep 19, 20212117337Passer rating through Week 2:Mac Jones: 96.7Trevor Lawrence: 57.1Zach Wilson: 56.1 https://t.co/hvMWOAhgKTNew Orleans Saints at New England PatriotsWhen: Sunday, September 26, 2021, at 1:00PM ESTWhere: Gillette Stadium, Foxborough, MassachusettsNew Orleans Saints at New England Patriots Betting OddsThe New England Patriots are 3 point favorites over the New Orleans Saints. The over/under is 42.5 points. The money line is +125 for the New Orleans Saints and -145 for the New England Patriots.New Orleans Saints at New England Patriots PicksThe Patriots do have a young offense with Jones under center, but they do have more opportunities to make plays happen than the Saints do. New Orleans is currently without their top wide receiver in Michael Thomas, and Winston's decision-making is sometimes questionable when under pressure.David Newton@DNewtonespnThis is impressive. The Panthers pressured Jameis Winston on 18 of his 28 dropbacks (64%), the third-highest pressure rate for any NFL team since ESPN began tracking pressure in 2009. It was the highest pressure rate Winston has ever faced. es.pn/3tV1y235:31 AM · Sep 19, 2021276101This is impressive. The Panthers pressured Jameis Winston on 18 of his 28 dropbacks (64%), the third-highest pressure rate for any NFL team since ESPN began tracking pressure in 2009. It was the highest pressure rate Winston has ever faced. es.pn/3tV1y23New Orleans Saints vs. New England Patriots Key InjuriesSaintsC Erik McCoy (Calf) doubtfulCB Marshon Lattimore (Hand) questionableG Calvin Throckmorten (Knee) questionableDE Payton Turner (Elbow) questionablePatriotsT Trent Brown (Calf) doubtfulRB Damien Harris (Finger) questionableLB Matt Judon (Knee) questionableSaints vs. Patriots Head to HeadThe Patriots have had success over the Saints since 1972. The Patriots are currently 10-4 in the series but are only 5-3 at home in Foxborough. Interesting to note though is that the New England Patriots have lost four of their last seven home games and were 1-3 versus NFC teams in 2020.Saints vs. Patriots PredictionThe Patriots will continue to build off the momentum that they had in Week 2 over the Jets and defeat the Saints. It will be a close game where the Patriots defense will get to Winston and the Saints early and often.Prediction:The New England Patriots will defeat the New Orleans Saints 28-7 to advance to 2-1 on the season.