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UFC Vegas 22: Brunson vs Holland is a mixed martial arts event produced by the Ultimate Fighting Championship that will take place on March 20, 2021 at the UFC APEX, Las Vegas United States.
| Weight Class | Fight Card | Method | Round | Results |
| Middleweight | Derek Brunson vs Kevin Holland | Decision | R5 (05:00) | Derek Brunson def. Kevin Holland |
| Heavyweight | Tai Tuivasa vs Harry Hunsucker | KO/TKO | R1 (00:49) | Tai Tuivasa def. Harry Hunsucker |
| Welterweight | Kenan Song vs Max Griffin | KO/TKO | R1 (02:20) | Max Griffin def. Kenan Song |
| Women Strawweight | Cheyanne Buys vs Montserrat Ruiz | Decision | R3 (05:00) | Montserrat Ruiz def. Cheyanne Buys |
| Bantamweight | Adrian Yanez vs Gustavo Lopez | KO/TKO | R3 (00:27) | Adrian Yanez def. Gustavo Lopez |
| Weight Class | Fight Card | Method | Round | Results |
| Women Bantamweight | Marion Reneau vs Macy Chiasson | Decision | R3 (05:00) | Macy Chiasson def. Marion Reneau |
| Lightweight | Leonardo Santos vs Grant Dawson | KO/TKO | R3 (04:59) | Grant Dawson def. Leonardo Santos |
| Middleweight | Trevin Giles vs Roman Dolidze | Decision | R3 (05:00) | Trevin Giles def. Roman Dolidze |
| Bantamweight | Montel Jackson vs Jesse Strader | KO/TKO | R1 (01:58) | Montel Jackson def. Jesse Strader |
| Flyweight | Bruno Silva vs JP Buys | KO/TKO | R2 (02:56) | Bruno Silva def. JP Buys |
Click to know about latest UFC Rankings.
