The game will be a battle between two quarterbacks on opposite ends of the spectrum in style and experience. Jalen Hurts, the Eagles' young, mobile quarterback will take on Tom Brady, the Buccaneers' steady, pocket passer who's the oldest quarterback ever to start a game.
Both teams are coming off wins in their previous games. The Buccaneers are hoping to extend their lead at the top of the NFC South, while the Eagles are hoping to get back to .500 after a poor start to the season.
Check out the injury report and the starting lineup for Thursday's game.
Tampa Bay Buccaneers vs. Philadelphia Eagles injury report
Tampa Bay Buccaneers
The Buccaneers will be missing some important players for Thursday's game against the Eagles. Star tight end Rob Gronkowski will miss his third straight game as he deals with internal injuries he sustained following a colossal hit during Week 3 against the Los Angeles Rams.
Safety Antoine Winfield Jr. is still in concussion protocol and while he's almost back to full health, a return on Thursday is a bit early.
Linebacker Lavonte David will miss the contest and this could swing the game in favor of the Eagles. The Buccaneers need every player they can to defend the pass, as they're vulnerable due to the injuries they have sustained in their secondary over the first few weeks of the season.
Most Eagles players are healthy and should be available for Thursday's game against the reigning champions. There are only two confirmed absentees.
Tight end Dallas Goedert was placed on the COVID-19 reserve list on Monday. He's vaccinated, so he had to test negative twice over 24 hours to be able to play. The Eagles have ruled him out.
Star right tackle Lane Johnson remains absent due to a personal matter. It's unclear if he's going to play in 2021.
Tampa Bay Buccaneers vs. Philadelphia Eagles starting lineup
Tampa Bay Buccaneers
QB - Tom Brady | RB - Leonard Fournette | WR - Chris Godwin, Antonio Brown, Mike Evans | TE - Cameron Brate | OL - Donovan Smith, Ali Marpet, Ryan Jensen, Alex Cappa, Tristan Wirfs
DL - Shaq Barrett, Ndamukong Suh, Vita Vea, Jason Pierre-Paul | LB - Devin White, K.J. Britt | CB - Jamel Dean, Richard Sherman, Ross Cockrell | S - Jordan Whitehead, Andrew Adams | K - Ryan Succop | P - Bradley Pinion
QB - Jalen Hurts | RB - Miles Sanders | WR - DeVonta Smith, Quez Watkins, Jalen Reagor | TE - Zach Ertz | OL - Andre Dillard, Landon Dickerson, Jason Kelce, Nate Herbig, Jordan Mailata
DL - Derek Barnett, Javon Hargrave, Fletcher Cox, Josh Sweat | LB - Eric Wilson, Alex Singleton | CB - Darius Slay, Steven Nelson, Avonte Maddox | S - Rodney McLeod, Anthony Harris | K - Jake Elliott | P - Arryn Siposs
Poll : Will the Eagles pull off an upset win the Buccaneers?