Pittsburgh Steelers vs. Minnesota Vikings predictions, odds, and picks for Week 4 showdown in Dublin

The Pittsburgh Steelers will face the Minnesota Vikings on Sunday for the NFL's first game in Europe this season. The teams head into the Week 4 clash on the back of wins and fans can expect an entertaining contest at Croke Park in Dublin.

With the Vikings without quarterback J.J. McCarthy for Sunday's game, let's examine predictions, odds and picks for the Week 4 showdown.

Pittsburgh Steelers vs. Minnesota Vikings: Game Details

Date and Time: Sunday, September 21, 2025, at 9:30 am ET

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Game: Pittsburgh Steelers vs. Minnesota Vikings

Venue: Croke Park, Dublin, Ireland

Pittsburgh Steelers vs. Minnesota Vikings: Betting Odds (DraftKings Sportsbook)

Moneyline: Pittsburgh Steelers (+130), Minnesota Vikings (-155)

Spread: Pittsburgh Steelers +2.5 (-102), Minnesota Vikings -2.5 (-118)

Total: 41.5 (Over/Under: -108/ -112)

Pittsburgh Steelers vs. Minnesota Vikings: Picks

The Vikings' defense enters the game following a dominant performance against the Cincinnati Bengals, which resulted in a blowout 48-10 win. Brian Flores’ defense will be up against the challenge of Aaron Rodgers, who has won 17 of his 30 starts against the Minnesota.

It is expected to be a low-scoring affair between the teams, looking for a second consecutive win and betting under will be the safe pick for this contest.

Pittsburgh Steelers vs. Minnesota Vikings: NFL Injury Report

Pittsburgh Steelers injury report

Alex Highsmith (ankle) - Out

Isaiahh Loudermilk (ankle) - Out

Will Howard (hand) - Out

Minnesota Vikings injury report

J. McCarthy (ankle) - Out

Aaron Jones (injured reserve) - Out

Blake Cashman (hamstring) - Out

C.J. Ham (undisclosed) - Out

Rondale Moore (knee) - Out

Pittsburgh Steelers vs. Minnesota Vikings: Prediction for Week 3

The two teams enter the contest having won their Week 3 matchups. It is expected to be an intense battle, with the Vikings holding the edge. One of Minnesota's shortcomings has been when teams run the ball against them.

It was on display during their Week 2 game against the Atlanta Falcons. While the Steelers can capitalize by optimizing their running game, they have not been up to the mark this season. Pittsburgh boasts a lowly 63.0 rushing yards per game and a 2.8 yards-per-carry average.

Despite McCarthy's absence, backup quarterback Carson Wentz is expected to power the Vikings over the line against the Steelers.

Score prediction: Minnesota Vikings 25, Pittsburgh Steelers 19

About the author

Chaitanya Prakash is an editor who covers US Sports at Sportskeeda. His first brush with sportswriting was in 2012 when the greatest football manager of all time, Sir Alex Ferguson, bid farewell to the beautiful game.

Although having started out professionally as a cricket writer in 2022, Chaitanya's curiosity and indiscriminate interest in all sports in general eventually introduced him to America's favorite pastime.

While Chaitanya's favorite player from the current crop is the dynamic Venezuelan Ronald Acuna Jr., his all-time favorite, however, is Pedro Martinez, for his self-belief and consistency. He also rates Jose Bautista's iconic bat flip in 2015 as his favorite moment in baseball history.

Chaitanya specializes in reporting on technical aspects of the game or analyzing patterns behind specific plays. He also likes pondering over players' self-assessments following the conclusion of a game as it helps him get an idea of how they think about the sport in general.

When not cheering for his favorites across sports, Chaitanya likes being transported to the past through a good war documentary or a historical documentary in general.

Know More

Vikings Nation! Check out the latest Minnesota Vikings Schedule and dive into the Vikings Depth Chart for NFL Season 2024-25.

Edited by Chaitanya Prakash