The LA Lakers go on the road for their next four games, starting with a matchup against the Minnesota Timberwolves on Wednesday at Target Center. This is the last game between the two teams in their season series with the Purple and Gold trailing 1-2.LeBron James and the Lakers are only 2-8 since the All-Star break. The two wins came at Crypto.com Arena, where LeBron James had back-to-back 50-point games. They’re currently hoping to end their 10-game road losing streak.While the Lakers have been horrible, the Timberwolves have been downright impressive in their last 10 games where they are 8-2. Minnesota, who is the 7th seed in the West, is giving the Denver Nuggets a run for their money for the coveted 6th spot and avoiding the play-in tournament.Minnesota Timberwolves@TimberwolvesWE ALL WITNESSED 𝙂𝙍𝙀𝘼𝙏𝙉𝙀𝙎𝙎.1:08 AM · Mar 16, 20226135375WE ALL WITNESSED 𝙂𝙍𝙀𝘼𝙏𝙉𝙀𝙎𝙎. https://t.co/3dFS7miXmOThe Minnesota Timberwolves Big 3 of Karl-Anthony Towns, D’Angelo Russell and Anthony Edwards are finding their rhythm at just the right time. They’re a young and hungry team who could potentially give the Lakers another long night on the road.Match DetailsFixture: LA Lakers vs Minnesota Timberwolves | 2021-22 NBA seasonDate & Time: Wednesday, March 16th; 8:00 PM ET (Thursday, March 17th; 5:30 AM IST)Venue: Target Center, Minneapolis, MNLA Lakers PreviewLeBron James and Russell Westbrook have to find better chemistry to carry the LA Lakers to the playoffs. [Photo: Forbes]LeBron James is undoubtedly the biggest story when it comes to the LA Lakers. Whether he scores at least 50 points or struggles, he can never get out of the spotlight. The four-time MVP has played 30 and 40 minutes, respectively, in their back-to-back losses to the Phoenix Suns and Toronto Raptors.NBA on ESPN@ESPNNBAWitnessing greatness @KingJames9:46 AM · Mar 14, 2022279593145Witnessing greatness 👑 @KingJames https://t.co/zQi7Dz1R0ZDespite calls to just shut it down, the Lakers franchise player keeps it going and could play heavy minutes against the Timberwolves. As much as the LA Lakers want to keep LeBron James fresh, doing so could cost them an all-important playoff spot.LA Lakers Predicted LineupG - Russell Westbrook | G - Malik Monk | F - Austin Reaves | F - LeBron James | C - Dwight HowardMinnesota Timberwolves PreviewThe Minnesota Timberwolves are peaking at just the right time. [Photo: Dunking with Wolves]Karl-Anthony Towns was the toast of the NBA just a few nights ago when he torched the San Antonio Spurs for 60 points, which were both career and franchise highs. He added 17 rebounds and three assists. Towns’ shooting abilities were on full display in the win as he made 19-31 shots, including an outstanding 7-11 from behind the arc.NBACentral@TheNBACentralKarl-Anthony Towns tonight: 60 points 17 rebounds 61% FGSHEESH11:04 AM · Mar 15, 2022129861238Karl-Anthony Towns tonight: 60 points 17 rebounds 61% FGSHEESH https://t.co/NOJpqZf4WZThe Timberwolves, however, are more than just a one-man show. They also have D’Angelo Russell and Anthony Edwards who can explode at any given time. Malik Beasley, Patrick Beverley and Jaylen Nowell also provide significant contributions for the sizzling-hot team.Minnesota Timberwolves Predicted LineupG - D’Angelo Russell | G - Patrick Beverley | F - Anthony Edwards | F - Jarred Vanderbilt | C - Karl-Anthony TownsLA Lakers vs Minnesota Timberwolves Betting Odds & SpreadsTeamsRecordMoney LineTotal Points (Over and Under)Point SpreadLA Lakers29-39+310Over 237 (-115)+9 (-110)Minnesota Timberwolves40-30 40-30 Under 237 (-105-9 (-110)Without Anthony Davis and the LA Lakers playing like a team 10 games below .500, there’s no question the Lakers are at a disadvantage. LA are a woeful 0-10 in their last 10 away from Crypto.com Arena, while the Minnesota Timberwolves are 22-12 on their home floor.In the last 10 games, the Timberwolves lead the league in defensive rating with 109.8, which is in contrast to the LA Lakers’ floundering 119.9 DRT. The Timberwolves are in their best form of the season and are hot on the Denver Nuggets’ heels for a better playoff seeding.The matchup is heavily leaning towards the Timberwolves, but LeBron James has been known to put on his Superman cape time and again to rescue the Lakers.Odds sourced from DraftKings SBLA Lakers vs Minnesota Timberwolves Betting TipsLA LakersLeBron James is averaging 32.8 points on 53.4% shooting from the field, including 39.8% from the three-point line.LA is perfect 2-0 against the spread when taken as underdogs by at least 8 points.The Lakers are 2-8 against the spread in the last 10 games.Click here to bet on the over/under for LeBron James’ scoring. Minnesota TimberwolvesThe Minnesota Timberwolves are 8-2 against the spreads in the last 10 games.Minnesota has left behind their opponents early in the game in 9 of their last 10 games.The Timberwolves are 5-3 against the spread when favored by at least 8 points.Click here to bet on the Minnesota Timberwolves getting to 15 points faster than the LA Lakers.Lakers vs Timberwolves Match PredictionThe Lakers are 2-8 in their last 10 games and needed LeBron James to erupt for at least 50 points in those games. They may have to ask the four-time NBA champion to have another historic night to pull off a win. If that were to happen, that may not be enough on the Minnesota Timberwolves home floor and with the Wolves’ Big 3 hitting their stride.25 of the Timberwolves' 70 games have gone over the 237 points total on Wednesday.Games involving the Lakers have gone over 237 points in 23 of their games this season.Minnesota is 24-3 against the spread when it hits at least 46.3% from the field. They are hitting 49.3% in their last 10 games.Click here to register and bet on the Lakers vs Timberwolves gameWhere to watch the Lakers vs Timberwolves gameThe NBA League Pass will stream the game live. Local coverage of the matchup is available via Spectrum SportsNet and BSN Sports.