San Antonio Spurs vs Dallas Mavericks Predicted Starting Lineups and Depth Charts for Oct. 22 | 2025-26 NBA Season

The San Antonio Spurs will head up I-35 on Wednesday to face the Dallas Mavericks at the American Airlines Center. The matchup will see the two Texan outfits renew their rivalry as both teams tip off their 2025-26 NBA campaigns.

The Spurs enter this campaign with optimism following a strong preseason. The team went unbeaten in five games, starting with a dominant 119-88 victory over the Guangzhou Loong Lions.

They followed it with a win against the Heat in Miami before securing a win against the Utah Jazz at home. The Spurs then wrapped up their preparations in style, securing back-to-back wins against the Indiana Pacers.

Similarly, the Dallas Mavericks enjoyed a successful preseason but were unable to remain unbeaten. Beginning their preparations with a 106-89 win against the reigning champions, their only loss came against the Charlotte Hornets in the following game.

However, they followed this loss with back-to-back wins against the Utah Jazz and the LA Lakers, leaving them with a 3-1 record. While their only major offseason addition was D’Angelo Russell, Dallas still boasts a well-balanced roster and will be eyeing a deep playoff push this season.

San Antonio Spurs vs. Dallas Mavericks Injury Reports

San Antonio Spurs injury report

Despite having plenty of positives to take from their preseason run, the Spurs start the season with numerous injuries. The team could be without four players for their season opener. De'Aaron Fox is set to be out until November with a hamstring issue, while Jeremy Sochan (wrist), Kelly Olynyk (heel) and Lindy Waters (eye) are out for their first game.

Dallas Mavericks injury report

The Mavericks will be without Kyrie Irving and Dante Exum for their opening game due to knee injuries. Meanwhile, Daniel Gafford is listed as doubtful with an ankle injury.

San Antonio Spurs vs. Dallas Mavericks Starting Lineups and Depth Charts

San Antonio Spurs starting lineups

The San Antonio Spurs do not have many options for their first game and should begin with their roster from their last preseason game. Stephon Castle and Julian Champagnie will likely make up the back court, while Devin Vassell and Harrison Barnes will start on the wings. Victor Wembanyama will feature as the lone center.

PG	Stephon Castle	Jordan McLaughlin
SG	Jullian Champiagne	Dylan Harper
SF	Devin Vassell	Keldon Johnson
PF	Harrison Barnes	Carter Bryant
C	Victor Wembanyama	Luke Kornet	Bismack Biyombo

Dallas Mavericks starting lineups

On the other hand, the Mavericks will start with D'Angelo Russell in Kyrie's absence, while Klay Thompson should help complete the backcourt. Copper Flagg will likely start his first NBA game as the small forward, while Anthony Davis and Dereck Lively II will start as the power forward and center, respectively.

PG	D'Angelo Russell	Brandon Williams	RJ Nembhard Jr.
SG	Klay Thompson	Max Christie
SF	Cooper Flagg	Naji Marshall	Caleb Martin
PF	Anthony Davis	PJ Washington
C	Dereck Lively II	Dwight Powell