UFC 259: Błachowicz vs. Adesanya is a mixed martial arts event produced by the Ultimate Fighting Championship that will take place on March 6, 2021 at the UFC Apex facility in Las Vegas, Nevada, United States.
UFC 259 Fight Card and Results
Main Fight Card
| Weight Class | Fight Card | Method | Round | Results |
| Light Heavyweight | Jan Blachowicz vs. Israel Adesanya | Decision | R5 (05:00) | Jan Blachowicz def. Israel Adesanya |
| Women Featherweight | Amanda Nunes vs. Megan Anderson | Submission | R1 (02:03) | Amanda Nunes def. Megan Anderson |
| Bantamweight | Petr Yan vs. Aljamain Sterling | Disqualification | R4 (04:29) | Aljamain Sterling def. Petr Yan |
| Lightweight | Islam Makhachev vs. Drew Dober | Submission | R3 (01:37) | Islam Makhachev def. Drew Dober |
| Lightweight | Thiago Santos vs. Aleksandar Rakić | Decision | R3 (05:00) | Aleksandar Rakić def. Thiago Santos |
Preliminary Fight Card
| Weight Class | Fight Card | Method | Round | Results |
| Bantamweight | Dominick Cruz vs. Casey Kenney | Decision | R3 (05:00) | Dominick Cruz def. Casey Kenney |
| Bantamweight | Song Yadong vs. Kyler Phillips | Decision | R3 (05:00) | Kyler Phillips def. Song Yadong |
| Flyweight | Joseph Benavidez vs. Askar Askarov | Decision | R3 (05:00) | Askar Askarov vs. Joseph Benavidez |
| Flyweight | Rogerio Bontorin vs. Kai Kara-France | KO/TKO | R1 (04:55) | Kai Kara-France def. Rogerio Bontorin |
Early Prelims Card
| Weight Class | Fight Card | Method | Round | Results |
| Flyweight | Tim Elliott vs. Jordan Espinosa | Decision | R3 (05:00) | Tim Elliott def. Jordan Espinosa |
| Light Heavyweight | Kennedy Nzechukwu vs. Carlos Ulberg | KO/TKO | R2 (03:19) | Kennedy Nzechukwu def. Carlos Ulberg |
| Welterweight | Sean Brady vs. Jake Matthews | Submission | R3 (03:28) | Sean Brady def. Jake Matthews |
| Women Strawweight | Livia Renata Souza vs. Amanda Lemos | KO/TKO | R1 (03:39) | Amanda Lemos def. Livia Renata Souza |
| Lightweight | Uros Medic vs. Aalon Cruz | KO/TKO | R1 (01:40) | Uros Medic def. Aalon Cruz |
| Bantamweight | Mario Bautista vs. Trevin Jones | KO/TKO | R2 (00:47) | Trevin Jones def. Mario Bautista |
