UFC 265: Lewis vs. Gane is a mixed martial arts event produced by the Ultimate Fighting Championship that took place on August 7, 2021 at the Toyota Center in Houston, Texas, United States.
Main Card
| Weight Class | Fights | Method | Round | Results |
| Heavyweight | Derrick Lewis vs. Ciryl Gane | KO/TKO | R3 (04:11) | Ciryl Gane def. Derrick Lewis |
| Bantamweight | José Aldo vs. Pedro Munhoz | Decision | R3 (05:00) | José Aldo def. Pedro Munhoz |
| Welterweight | Michael Chiesa vs. Vicente Luque | Submission | R1 (03:25) | Vicente Luque def. Michael Chiesa |
| Women Strawweight | Tecia Torres vs. Angela Hill | Decision | R3 (05:00) | Tecia Torres def. Angela Hill |
| Bantamweight | Song Yadong vs. Casey Kenney | Decision | R3 (05:00) | Song Yadong def. Casey Kenney |
Preliminary Card
| Weight Class | Fights | Method | Round | Results |
| Lightweight | Bobby Green vs. Rafael Fiziev | Decision | R3 (05:00) | Rafael Fiziev def. Bobby Green |
| Bantamweight | Vince Morales vs. Drako Rodriguez | Decision | R3 (05:00) | Vince Morales def. Drako Rodriguez |
| Light Heavyweight | Alonzo Menifield vs. Ed Herman | Decision | R3 (05:00) | Alonzo Menifield def. Ed Herman |
| Women Strawweight | Karolina Kowalkiewicz vs. Jessica Penne | Submission | R1 (04:32) | Jessica Penne def. Karolina Kowalkiewicz |
Early Prelims
| Weight Class | Fights | Method | Round | Results |
| Flyweight | Manel Kape vs. Ode Osbourne | KO/TKO | R1 (04:44) | Manel Kape def. Ode Osbourne |
| Bantamweight | Miles Johns vs. Anderson Dos Santos | KO/TKO | R3 (01:16) | Miles Johns def. Anderson Dos Santos |
| Women Flyweight | Victoria Leonardo vs. Melissa Gatto | KO/TKO | R2 (05:00) | Melissa Gatto def. Victoria Leonardo |
| Bantamweight | Johnny Muñoz vs. Jamey Simmons | Submission | R2 (02:35) | Johnny Muñoz def. Jamey Simmons |
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