After their Week 1 loss to the Pittsburgh Steelers, the Buffalo Bills have had two dominating wins in their last two matches, getting right back to the top of the AFC East like last season.While the passing game, led by Josh Allen, has been vital for the Bills, Stefon Diggs hasn't been a critical contributor. Veteran wide receiver Emmanuel Sanders has shown just why Buffalo was so keen on signing him this offseason.For the Houston Texans, Tyrod Taylor's performance in Week 1 and an early-season win gave fans a lot of hope. However, after Taylor suffered an injury, the Texans went with rookie Davis Mills and the team has lost two straight. Daily Deshaun Watson trade rumors have also hindered the Texans.The Buffalo Bills will now host the Houston Texans this Sunday to advance to 3-1. The Texans will avoid dropping to 1-3 and hope to get a bounce-back win.Houston Texans at Buffalo BillsWhen: Sunday, October 3, 2021, at 1:00 PM ESTWhere: Highmark Stadium, Orchard Park, New YorkHouston Texans at Buffalo Bills Betting OddsSpreadsBills: +16.5 (-110)Texans: -16.5 (-110)MoneylineBills: -1400Texans: +750TotalsBills: o48.5 (-110)Texans: u48.5 (-110)Buffalo Bills@BuffaloBillsWe’re LIVE with the AFC Offensive Player of the Week.Comment below to congratulate @JoshAllenQB!#HOUvsBUF | #BillsMafia twitter.com/i/broadcasts/1…2:21 AM · Sep 29, 202135921We’re LIVE with the AFC Offensive Player of the Week.Comment below to congratulate @JoshAllenQB!#HOUvsBUF | #BillsMafia twitter.com/i/broadcasts/1…Houston Texans at Buffalo Bills PicksThis game may end up a bit lopsided because of where each team currently stands. For the Bills, it has seemed that they have found their groove the last two weeks, and opponents haven't scored more than 23 points against them so far this season.For the Texans, it has been a struggle with a rookie quarterback under center. The Texans' defense will need to stop the Bills' offense even to have a chance.Houston Texans vs. Buffalo Bills Key InjuriesTexansWR Danny Amendola (thigh) doubtfulS Justin Reid (knee) is questionableCB Terrance Mitchell (concussion) is questionableQB Deshaun Watson (inactive)BillsS Micah Hyde (Quad) questionableG Jon Feliciano (concussion) doubtfulCB Taron Johnson (Groin) doubtfulS Jordan Poyer (ankle) doubtfulNFL on CBS 🏈@NFLonCBSRookie Passer Rating1. Davis Mills 80.92. Mac Jones 79.13. Trevor Lawrence 60.34. Zach Wilson 51.65. Justin Fields 39.9*minimum 35 pass attempts2:13 AM · Sep 30, 20211202175Rookie Passer Rating1. Davis Mills 80.92. Mac Jones 79.13. Trevor Lawrence 60.34. Zach Wilson 51.65. Justin Fields 39.9*minimum 35 pass attempts https://t.co/hpFQYXQeozTexans vs. Bills Head to HeadThe Houston Texans and Buffalo Bills last met in the Wild Card Round of the 2019 NFL playoffs. The Texans won that matchup 22-19, advancing to the next round and sending the Bills home. Both teams have met ten times and the Texans lead the series 6-4.Texans vs. Bills PredictionThis will be Davis Mills' first start on the road, and being that it's the Bills Mafia crowd, it won't be an easy task. The inexperience and a hostile environment will be a tall task for the rookie quarterback and the Texans.Prediction:The Buffalo Bills will defeat the Houston Texans 42-17 to improve to 3-1 and keep the top stop in the AFC East.