Fantasy Football is well underway after the conclusion of the NFL's opening week of the 2022 season, and there is already a sense of who will have a strong year.Ahead of Week 2, which begins with a mouth-watering Thursday Night Football clash between AFC heavyweights the Kansas City Chiefs and the Los Angeles Chargers, there is an awful lot of chopping and changing to be done to people's Fantasy Football teams.It's after Week 1 where Fantasy players generally tend to realize that they've made huge mistakes and look to start from scratch. As such, there will be plenty of players dropped following dismal Week 1 displays that you can pick up to transform your roster.Here are five game-changing Fantasy Football picks ahead of NFL Week 2:#1 - Tua Tagovailoa, Miami DolphinsTua could cause a Fantasy surprise in Week 2A 20-7 victory over Bill Belichick's New England Patriots is never something Miami Dolphins fans aren't going to enjoy to the maximum. However, there are still lingering doubts over Tua Tagovailoa.The quarterback wasn't great against the Pats, making several throws he is expected to make while inviting unnecessary pressure on multiple occasions.It was a performance that was a reasonable start to the season, but now is the time for Fantasy players to take advantage of his availability and a favorable matchup.Marcel Louis-Jacques@Marcel_LJI missed this in real time on Tua’s TD to Waddle:- Watch Tua’s subtle movement immediately after the snap, just a little flinch to his left as he looks off Ja’Whaun Bentley (8)- That gets Bentley out of the way and creates just enough space for Waddle after the catch1527189I missed this in real time on Tua’s TD to Waddle:- Watch Tua’s subtle movement immediately after the snap, just a little flinch to his left as he looks off Ja’Whaun Bentley (8)- That gets Bentley out of the way and creates just enough space for Waddle after the catch https://t.co/tVLKiIPQqrIn Week 2, the Dolphins will take on a Baltimore Ravens team who won their opener against the New York Jets, yet the stats tell a story that Fantasy players may wish to analyze.The Ravens' defense was poor against the Jets as they gave up more yards in both the passing and rushing games than they produced on offense.Robert Saleh has a generally unrefined offense at this stage in his tenure in New York, and you'd expect the Dolphins to enjoy more success.One bright spot from the victory over New England was the connection between Tagovailoa and Tyreek Hill. There were numerous completions to the new No. 1 wide receiver, and exploiting this against a soft Ravens defense could lead to points on Sunday.#2 - AJ Dillon, Green Bay PackersThe Green Bay Packers need to bounce back against the BearsGreen Bay had an awful Week 1 and will be looking to make amends immediately in meeting with fierce rivals, the Chicago Bears.The Bears won against the San Francisco 49ers, but their defense was very vulnerable to the run, giving up 176 rushing yards. In a humbling at the hands of the Vikings, Green Bay's only positive was the 111 rushing yards they racked up.AJ Dillon will get a lot of carries in point-scoring situations when the Packers meet the Bears, and he could score many Fantasy points as a result.