Bills vs Washington prediction, odds and picks - September 26

The Buffalo Bills entered the 2021 NFL season as clear favorites to challenge the Kansas City Chiefs for the AFC title. After a tough Week 1 loss to the Pittsburgh Steelers, where both Josh Allen's offense and the team's defense looked off, the Bills rebounded in a big way in a 35-0 rout of the Miami Dolphins.

The Washington Football Team, on the other hand, lost starting quarterback Ryan Fitzpatrick in Week 1 against the Los Angeles Chargers. Taylor Heinicke made the start against the New York Giants last Thursday night, as a game-winning field goal secured Washington's first win of the season.

With both Washington and the Bills at 1-1, who will advance to 2-1 and who will fall to a losing record after Week 3?

Looking to predict NFL playoff Scenarios? Try our NFL Playoff Predictor for real-time simulations and stay ahead of the game!

Washington Football Team vs Buffalo Bills schedule

When: Sunday, September 26 at 1:00 PM EST

Where: Highmark Stadium, Orchard Park, New York

Washington Football Team vs Buffalo Bills betting odds

The Buffalo Bills are 7.5-point favorites over Washington. The over/under is 45.5 points. The money line is +280 for Washington and -350 for the Buffalo Bills.

Washington Football Team vs Buffalo Bills picks

The Buffalo Bills were able to shut out the Miami Dolphins last week, and while that might not happen again, the Bills defense could hold the Washington offense at bay.

Taylor Heinicke was impressive last season and equally impressive last week, when he had to take over the reins. But whether Heinicke and the offense will be able to get one past a tough Bills defense that prides itself on combating the running and passing game seems a bit of a tall order.

Washington vs Buffalo Bills key injuries

Washington

RB Antonio Gibson (shoulder) questionable
DT Matt Ioannidis (knee) questionable

Buffalo Bills

DE Efe Obada (calf) questionable
DT Star Lotulelei (groin) questionable
WR Gabriel Davis (ankle) questionable
S Micah Hyde (neck) questionable
CB Dane Jackson (knee) questionable
CB Levi Wallace (knee) questionable

Washington vs Buffalo Bills Head to Head

The Bills have have won seven of the last eight matchups between the two teams. Buffalo also leads the series 9-6. The last time these two teams met was in 2019, when the Bills defeated Washington 24-9.

Washington vs Buffalo Bills predictions

The Washington Football Team won't be able to get a road win over the Buffalo Bills and will fall to 1-2 on the season. The Bills will look more like themselves and advance to 2-1.

Prediction:

The Buffalo Bills will defeat the Washington Football Team with a 38-14 win at home.

Also check out: Complete Thursday Night Football Schedule 2021

About the author

Bethany Cohen is an NFL writer at Sportskeeda, with a rich prior 15-year experience in the sports writing industry, primarily covering the MLB and MiLB. She majored in Communications from the University of South Florida and has previously worked for top companies such as Examiner.com and Legends on Deck.

Bethany owes her NFL allegiance to the Pittsburgh Steelers owing to their long-standing tradition and competitiveness. She is a fan of old stalwarts such as Terry Bradshaw and Franco Harris and would love to watch them in the 1970s if she manages to get her hand on a time machine. She also acknowledges the greatness of modern icons like T.J. Watt for his desire to continuously improve despite being on top. She admires coaches Mike Tomlin and Andy Reid for their longevity and success.

The ace reporter credits her knowledge and love for the sport to be her biggest reporting strengths. Prior fact-checking is a big component of her process and she always scours through additional sources to ensure complete accuracy in her content.

Super Bowl XLIII, when the Steelers won the the grand prize after Santonio Holmes’ epic catch in the end zone with just seconds left on the clock is etched in Bethany’s memory forever. When she is free of her professional commitments, she likes to attend sports events and music concerts.

Know More

Buffalo Bills Nation! Check out the latest Buffalo Bills Schedule and dive into the latest Bills Depth Chart for NFL Season 2024-25.

Edited by Colin D'Cunha

Bills vs Washington prediction, odds and picks - September 26 | NFL Season 2021-22