It's that time of the week again in fantasy football where you take a look at your lineup and see where there is a need through the waiver wire. Maybe you had JuJu Smith-Schuster or Saquon Barkley and now have holes in your team with their injuries. The waiver wire is an opportunity to snag a trending player or an inside tip before others in your league. Injuries remain an issue as the league preps for Week 6. Here are five players to try to target on the waiver wire, as they should be available in most standard leagues.Top Five Fantasy football Week 6 Waiver Wire Pickups#1 - RB Devontae Booker, New York GiantsOvertime@overtimeNice one handed snag by Devontae Booker 😮(via @NFL)5:08 AM · Sep 12, 202128731Nice one handed snag by Devontae Booker 😮(via @NFL) https://t.co/ODCIDrMiEfSaquon Barkley suffered a nasty ankle sprain on Sunday and will be out for Week 6 against the LA Rams. Devontae Booker had 20 points in fantasy football as a replacement for Barkley and will be an RB2/3 option to look into, especially if you have Saquon Barkley. Booker will take on the majority of the carries, with Gary Brightwell likely serving as a pass-catcher. The LA Rams aren't ranked so high on defense this year and could allow Devontae Booker a good outing. LA's offense will win the game, but Booker could end up with at least 12 fantasy football points in Week 6.#2 - TE Ricky Seals-Jones, Washington Football TeamPro Football Network@PFN365Ricky Seals-Jones could be a sneaky play at the tight end position this week for fantasy managers.2:13 AM · Oct 12, 20213Ricky Seals-Jones could be a sneaky play at the tight end position this week for fantasy managers.https://t.co/1gaY9s3kWiLogan Thomas remains out until at least Week 8 while on IR, which means Ricky Seals-Jones will continue to have a large role on the offense. Week 6 has Washington facing the Kansas City Chiefs, who have a vulnerable defense. Taylor Heinicke could have a good game against the Chiefs and Seals-Jones will be a favorite target across the middle and on short passes. Expect at least ten targets for the tight end and upwards of 15 points in fantasy football.#3 - TE Dan Arnold, Jacksonville JaguarsMike Clay@MikeClayNFLDan Arnold 83% snap share per @NextGenStats Leads Jags with 48 receiving yards3:13 AM · Oct 10, 2021283Dan Arnold 83% snap share per @NextGenStats Leads Jags with 48 receiving yardsDallas Goedert, Maxx Williams and George Kittle are a handful of top tight ends who have suffered serious injuries and the position has never been known to be deep. Dan Arnold led the Jacksonville Jaguars in Week 5 with eight targets, six catches and 64 yards. The offense is struggling without DJ Chark Jr. and Dan Arnold could hover around nine targets per game on average.#4 - WR James Washington, Pittsburgh Steelers𝙇𝙤𝙣𝙙𝙤𝙣²²@NajeeErait’s james washington time11:14 AM · Oct 11, 202114711it’s james washington time https://t.co/AXUnZfOxCrJames Washington is expected to be back from a groin injury for Week 6, just in time to replace JuJu Smith-Schuster as a starter. Washington had ten fantasy football points in Week 4 from four catches and 69 yards, but he's now going to be used much more often. Pittsburgh's offense seems to have finally turned the corner in 2021 and should be a bit more exciting, especially with a playmaker like Washington on the field.#5 - QB Davis Mills, Houston TexansPFF HOU Texans@PFF_TexansDavis Mills PFF Grade 🟥 Weeks 2-4: 35.1 🟥 Week 5: 85.9 HUGE IMPROVEMENT FROM THE ROOKIE ‼️5:06 AM · Oct 12, 20215814Davis Mills PFF Grade 🟥 Weeks 2-4: 35.1 🟥 Week 5: 85.9 HUGE IMPROVEMENT FROM THE ROOKIE ‼️ https://t.co/L8n4l7qBiLThe rookie had 24 points in fantasy football against the New England Patriots in Week 5. Davis Mills threw for three touchdowns and almost upset the Patriots. Many people will continue to overlook Mills, but he's worth picking up in deep fantasy football leagues as a QB2. The Indianapolis Colts made Lamar Jackson look like Aaron Rodgers on Monday night and could allow Mills to have another strong showing against a weakened defense.